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Phalloidin

Phalloidin

Product ID P2304
Cas No. 17466-45-4
Purity ≥90%
Product Unit SizeCostQuantityStock
1 mg $410.30 In stock
5 mg $1,735.80 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Phalloidin is a phallotoxin found in Amanita phalloides that exhibits cytotoxic activity. Phalloidin binds F-actin and inhibits depolymerization; it locks adjacent subunits together, preventing actin ATP hydrolysis. Fluorescent-tagged conjugates of phalloidin are used to measure distribution of F-actin in vitro.

Product Info

Cas No.

17466-45-4

Purity

≥90%

Formula

C35H48N8O11S

Formula Wt.

788.87

Chemical Name

Cyclic(L-alanyl-D-threonyl-L-cysteinyl-cis-4-hydroxy-L- prolyl-L-alanyl-2-mercapto-L-tryptophyl-4,5-dihydroxy-L- leucyl), cyclic (3,6)-sulfide

IUPAC Name

28-(2,3-dihydroxy-2-methylpropyl)-18-hydroxy-34-(1-hydroxyethyl)-23,31-dimethyl-12-thia-10,16,22,25,27,30,33,36-octazapentacyclo[12.11.11.03,11.04,9.016,20]hexatriaconta-3(11),4,6,8-tetraene-15,21,24,26,29,32,35-heptone

Synonym

Phalloidine

Melting Point

280-282°C

Solubility

Soluble in methanol, ethanol, butanol, pyridine or hot water.

Appearance

White powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

P2304 MSDS PDF

Info Sheet

P2304 Info Sheet PDF

References

Cooper JA. Effects of cytochalasin and phalloidin on actin. J Cell Biol. 1987 Oct;105(4):1473-8. PMID: 3312229.

Barden JA, Miki M, Hambly BD, et al. Localization of the phalloidin and nucleotide-binding sites on actin. Eur J Biochem. 1987 Feb 2;162(3):583-8. PMID: 3830158.

Custom Order

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