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Apoptosis Activator 2

Apoptosis Activator 2

Product ID A6058
Cas No. 79183-19-0
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $75.10 In stock
5 mg $135.00 In stock
10 mg $245.10 In stock
50 mg $759.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Apoptosis activator 2 displays neuromodulatory and anticancer activities, induces apoptosis and cell death in gastric adenocarcinoma cells and neurons. This compound is used to study apoptosis in cancer research and neurodegenerative diseases.

Product Info

Cas No.

79183-19-0

Purity

≥98%

Formula

C15H9Cl2NO2

Formula Wt.

306.14

IUPAC Name

1-(3,4-Dichlorobenzyl)-1H-indole-2,3-dione

Synonym

AA-2, Apoptosis activator II, AA-II, AAII, N-(3,4-dichlorobenzyl) Isatin, MDK83190

Solubility

DMSO 61 mg/mL (199.25 mM) Water Insoluble Ethanol Insoluble

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A6058 MSDS PDF

Info Sheet

A6058 Info Sheet PDF

References

Kim JH, Lee J. Induced neural stem cells protect neuronal cells against apoptosis. Med Sci Monit. 2014 Dec 22;20:2759-66. PMID: 25554259.

Farivar TN, Najafipour R, Johari P. Nano - drug Delivery of Apoptosis Activator 2 to AGS Cells by Liposomes Conjugated with Anti-TROP2 Antibody. N Am J Med Sci. 2012 Nov;4(11):582-5. PMID: 23181231.

Nguyen TV, Jayaraman A, Quaglino A, et al. Androgens selectively protect against apoptosis in hippocampal neurones. J Neuroendocrinol. 2010 Sep;22(9):1013-22. PMID: 20561156.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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