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PHT-427

Product ID P3076
Cas No. 1191951-57-1
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $67.80 In stock
10 mg $107.40 Please Inquire
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  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

PHT-427 is an inhibitor of PDK1 and Akt that exhibits anticancer chemotherapeutic activity, inhibiting tumor growth in animal models of breast cancer and non-small cell lung cancer (NSCLC).

Product Info

Cas No.

1191951-57-1

Purity

≥98%

Formula

C20H31N3O2S2

Formula Wt.

409.61

Chemical Name

4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide

IUPAC Name

4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide

Synonym

PHT427; PHT 427

Solubility

DMSO 82 mg/mL (200.19 mM) Ethanol 60 mg/mL (146.48 mM) Water Insoluble

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

P3076 MSDS PDF

Info Sheet

P3076 Info Sheet PDF

Brochures

PI3K-Akt-mTORC Pathway Booklet

References

Meuillet EJ, Zuohe S, Lemos R, et al. Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor. Mol Cancer Ther. 2010 Mar;9(3):706-17. PMID: 20197390.

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