Description
Argatroban is an antithrombotic/anticoagulant compound that inhibits thrombin. Argatroban is clinically used to treat thrombosis and acute coronary syndrome.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Argatroban is an antithrombotic/anticoagulant compound that inhibits thrombin. Argatroban is clinically used to treat thrombosis and acute coronary syndrome.
| Cas No. | 74863-84-6 |
|---|---|
| Purity | ≥98% |
| Formula | C23H36N6O5S |
| Formula Wt. | 508.64 |
| Chemical Name | (2R,4R)-4-Methyl-1-((S)-N(sup2)-(((RS)-1,2,3,4- tetrahydro-3-methyl-8-quinolyl)sulfonyl)arginyl)- pipecolic acid |
| IUPAC Name | (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3, 4-tetrahydroquinolin-8-yl)sulfonylamino]pentanoyl]-4-methylpiperidine-2- carboxylic acid |
| Synonym | Argatrobanum |
| Melting Point | 188-191°C |
| Solubility | Soluble in ethanol. |
| Appearance | White Crystalline Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Sobky S, Fawzy I, Ahmed M, et al. Drug repurposing of argatroban, glimepiride, and ranolazine shows anti-SARS-CoV-2 activity via diverse mechanisms. Heliyon. 2025 Jan 10;11(3):e41894. PMID: 39968139.
Tardy-Poncet B, Combe M, Piot M, et al. Effects of argatroban, danaparoid, and fondaparinux on trombin generation in heparin-induced thrombocytopenia. Thromb Haemost. 2013 Mar;109(3):504-9. PMID: 23328916.
Cruz-González I, López-Jiménez R, Perez-Rivera A, et al. Pharmacokinetic evaluation of argatroban for the treatment of acute coronary syndrome. Expert Opin Drug Metab Toxicol. 2012 Nov;8(11):1483-93. PMID: 22970706.
Ca2+-sensing receptor antagonist.
ATR inhibitor.
Found in Ginkgo; HIV protease and fatty acid sy...
Endogenous peptide, involved in paracrine and a...
Peptide, alters uterine contractility; V1/2 and...
HDM2 inhibitor
Dicarboxylic acid found in Arabidopsis; PPARγ ...
Tricyclic benzonaphthyridinone; mTORC1/2 inhibi...
Pyridopyrimidinone; PI3K and mTOR inhibitor.
Non-steroid; AR antagonist.
Found in plants in Astragalus, Allium, and Bras...
T-type Ca2+ and voltage-gated Na+ channel block...
Macrolide antibiotic; peptidyl transferase inhi...
Isoflavone found in Pueraria; 5-HT2C and GABA-A...
Glucocorticoid
Endogenous tachykinin peptide, involved in infl...
Flavonol glycoside originally found in Epimediu...
FXR agonist.
p110δ PI3K inhibitor.
Synthesis impurity