Description
AZD-8330 is an inhibitor of MEK1/2 that exhibits anticancer chemotherapeutic activity. AZD-8330 is currently in clinical trials for the treatment of advanced stage cancers.
AZD-8330
Product ID A9715
Cas No. 869357-68-6
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 869357-68-6 |
|---|---|
| Purity | ≥98% |
| Formula | C16H17FlN3O4 |
| Formula Wt. | 461.23 |
| IUPAC Name | 2-(2-fluoro-4-iodoanilino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxopyridine-3-carboxamide |
| Synonym | ARRY-704, ARRY-424704 |
| Solubility | DMSO 92 mg/mL (199.46 mM) Ethanol 92 mg/mL (199.46 mM) Water Insoluble |
| Appearance | White Powder |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
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| Info Sheet | |
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References
Cohen RB, Aamdal S, Nyakas M, et al. A phase I dose-finding, safety and tolerability study of AZD8330 in patients with advanced malignancies. Eur J Cancer. 2013 May;49(7):1521-9. PMID: 23433846.
Akinleye A, Furqan M, Mukhi N, et al. MEK and the inhibitors: from bench to bedside. J Hematol Oncol. 2013 Apr 12;6:27. PMID: 23587417.