• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
BAY80-6946 Hydrochloride

BAY80-6946 Hydrochloride

Product ID B0397
Cas No. 1402152-13-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $77.80 In stock
5 mg $162.30 In stock
10 mg $292.00 In stock
50 mg $648.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

BAY80-6946 is an inhibitor of p110α PI3K that exhibits anticancer chemotherapeutic activity. BAY80-6946 is currently in clinical trials and shows some benefit in the treatment of pancreatic cancer. In cellular and animal models of multiple myeloma, BAY80-6946 inhibits cell cycle progression, induces apoptosis, and inhibits cell proliferation and tumor growth.

Product Info

Cas No.

1402152-13-9

Purity

≥98%

Formula

C23H30Cl2N8O4

Formula Wt.

553.45

Chemical Name

2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide;dihydrochloride

IUPAC Name

2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide;dihydrochloride

Synonym

Copanlisib HCl, BAY80-6946 HCl; Copanlisib dihydrochloride; UNII-03ZI7RZ52O; 03ZI7RZ52O

Solubility

Soluble in water (20 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

B0397 MSDS PDF

Info Sheet

B0397 Info Sheet PDF

References

Glauer J, Pletz N, Schön M, et al. A novel selective small-molecule PI3K inhibitor is effective against human multiple myeloma in vitro and in vivo. Blood Cancer J. 2013 Sep 6;3:e141. PMID: 24013662.

Cheng H, Merika E, Syrigos KN, et al. Novel agents for the treatment of pancreatic adenocarcinoma. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011. JOP. 2011 Jul 8;12(4):334-8. PMID: 21737890.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C3352

    Cinacalcet Hydrochloride

    Ca2+-sensing receptor agonist.

    ≥99%
  • R3477

    Ritodrine Hydrochloride

    Phenylethylamine; β2-adrenergic agonist, SK/BK...

    ≥98%
  • B0133

    Baicalin

    Flavone found in Scutellaria; prolyl oligopepti...

    ≥95%
  • P9869

    Pyridoxine Hydrochloride

    Vitamin B6 derivative, antioxidant.

    ≥98%
  • C281006

    Chaetocin

    Chaetocin is naturally produced by Chaetomium s...

    ≥98%
  • N8277

    Nutlin-3

    Imidzoline derivative; MDM2 inhibitor.

    ≥95%
  • A1017

    Aceclofenac

    Diclofenac analog, NSAID; COX-2 inhibitor.

    ≥98%
  • P1754

    Penciclovir

    Nucleoside (guanosine) analog; DNA chain termin...

    ≥98%
  • P5885

    Povidone Iodine

    Polyvinyl pyrrolidone polymer, disinfectant.

    ≥98%
  • A7668

    Atracurium Besylate

    Non-depolarizing NMJ blocker; AChR antagonist.<...

    ≥95%
  • B8277

    Butein

    Flavonoid found in Rhus verniciflua and Butea m...

    ≥99%
  • P5747

    Polymyxin B sulfate

    Cationic lipid polypeptide, mixture of polymyxi...

    ≥6500 iu/mg
  • A0534

    Abiraterone

    Progesterone derivative; Cyp17A1 inhibitor.

    ≥99%
  • A9662

    AZ-628

    B-Raf and c-Raf inhibitor.

    ≥96%
  • T7132

    Triacetyl Resveratrol

    Resveratrol prodrug; potential SIRT1 activator....

    ≥99%
  • G124088

    GDC-1971

    SHP2 inhibitor

    ≥99%
  • O1200

    Odanacatib

    Cathepsin K inhibitor.

    ≥99%
  • A5280

    Angiotensin II (3-8), human

    Endogenous peptide fragment, involved in vasoco...

    ≥95%
  • T2833

    1-Thio-β-D-glucose Tetraacetate

    Imaging agent; Maillard reaction inhibitor.

    ≥98%
  • A3208

    AICAR

    AMPK activator.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only