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Big Endothelin-1 (1-38), human

Product ID B3324
Cas No. 124363-98-0
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $630.30 Please Inquire
1 mg $1,072.90 Please Inquire
2.5 mg $1,891.20 Please Inquire
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  • Description
  • Product Info
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  • Description
  • Product Info
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  • References
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Description

Big endothelin-1 is a cleavage precursor to endothelin-1; secretion of this peptide is stimulated by angiotensin II (AT II) and thrombin. Like endothelin-1, big endothelin-1 exhibits vasoconstrictive/hypertensive activity, increasing arteriolar constriction and decreasing blood flow.

Product Info

Cas No.

124363-98-0

Purity

≥95%

Formula

C189H282N48O56S5

Formula Wt.

4282.96

Solubility

Soluble in 0.1% TFA. Soluble in 0.5% acetic acid.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

B3324 Info Sheet PDF

References

Lawrence E, Brain SD. Big endothelin-1 and big endothelin-3 are constrictor agents in the microvasculature: evidence for the local phosphoramidon-sensitive conversion of big endothelin-1. Eur J Pharmacol. 1993 Mar 23;233(2-3):243-50. PMID: 8467870.

Kohno M, Yasunari K, Yokokawa K, et al. Inhibition by atrial and brain natriuretic peptides of endothelin-1 secretion after stimulation with angiotensin II and thrombin of cultured human endothelial cells. J Clin Invest. 1991 Jun;87(6):1999-2004. PMID: 1645748.

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