Description
Blasticidin S is an antibiotic that also exhibits anti-parasitic activity. Blasticidin S inhibits protein synthesis by inducing deformations in P-site tRNA. Blasticidin S inhibits aflatoxin production in species of Aspergillus.
Blasticidin S Hydrochloride
Product ID B4402
Cas No. 3513-03-9
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 3513-03-9 |
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| Purity | ≥98% |
| Formula | C17H26N8O5 • HCl |
| Formula Wt. | 458.5 |
| IUPAC Name | (2S,3S,6R)-3-[[(3S)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid;hydrochloride |
| Melting Point | 224-225°C(dec) |
| Solubility | Soluble in water. Insoluble in organic solvents. |
| Appearance | White to off white powder |
Shipping and Storage
| Store Temp | 4°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Yoshinari T, Sakuda S, Watanabe M, et al. New metabolic pathway for converting blasticidin S in Aspergillus flavus and inhibitory activity of aflatoxin production by blasticidin S metabolites. J Agric Food Chem. 2013 Aug 21;61(33):7925-31. PMID: 23879927.
Svidritskiy E, Ling C, Ermolenko DN, et al. Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12283-8. PMID: 23824292.