• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Clioquinol

Clioquinol

Product ID C451338
Cas No. 130-26-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $61.40 In stock
5 g $149.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Clioquinol is an antifungal agent that has exhibited neuroprotective and anticancer properties. It is a metal ionophore that inhibits growth of pathogenic fungi including strains of Candida and Aspergillus.

Treatment using clioquinol in models of Huntington’s disease in mice resulted in improved behavioral and pathologic phenotypes and extension of life span. The structural and functional features of clioquinol as a metal chelating aggregation modulator have been adapted in combination with epigallocatechin gallate to create a hybrid modulator that prevents the generation of reactive oxygen species and interrupting the interaction of toxic amyloid-beta species with mitochondria, making it a potential treatment for Alzheimer’s disease.

Product Info

Cas No.

130-26-7

Purity

≥98%

Formula

C9H55ClINO

Formula Wt.

305.50

IUPAC Name

5-chloro-7-iodoquinolin-8-ol

Synonym

5-Chloro-7-iodoquinolin-8-ol, Iodochlorhydroxyquin, Chinoform Chloroiodoquin, 5-Chloro-8-hydroxy-7-iodoquinoline

Solubility

Practically insoluble in water and in ethanol.

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C451338 MSDS PDF

Info Sheet

C451338 Info Sheet PDF

References

You Z., Ran X., et al. Clioquinol, an alternative antimicrobial agent against common pathogenic microbe. J Mycol Med. 28(3):492-501 (2018). PMID: 29650464.

Nguyen T., Hamby A., et al. Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model. Proc Natl Acad Sci. 102(33):11840-11845 (2005). PMID: 16087879.

Rajasekhar K., Mehta K., et al. Hybrid Multifunctional Modulators Inhibit Multifaceted Aβ Toxicity and Prevent Mitochondrial Damage. ACS Chem Neurosci. 9(6):1432-1440 (2018). PMID: 29557650.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E2003

    Efavirenz

    Non-nucleoside RT inhibitor.

    ≥99%
  • F4503

    Flavokawain B

    Chalcone kavalactone that suppresses inflammati...

    ≥97%
  • G4634

    Glipizide

    Sulfonylurea; ATP-sensitive K+ channel blocker....

    ≥98%
  • A0963

    Adrenocorticotropic Hormone (1-10), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • P0013

    P7C3

    Aminopropyl carbazole, neuroprotective.

    ≥98%
  • S8243

    Sulbactam Sodium

    β-lactamase inhibitor.

    ≥98%
  • I1400

    Idarubicin Hydrochloride

    Anthracycline, DNA intercalator; topoisomerase ...

    ≥98%
  • L960010

    LY-3200882

    TGF-β1 inhibitor.

    ≥98%
  • M9634

    Myriocin

    Atypical amino acid found in Isaria sinclairi, ...

    ≥99%, TLC
  • A0401

    Abacavir

    Nucleoside (guanosine) analog; RT, guanylyl cyc...

    ≥98%
  • W4096

    WKYMVM-NH2

    Synthetic peptide; FPRL1 agonist.

    ≥95%
  • V1600

    VE-821

    ATR inhibitor.

    ≥98%
  • V7200

    VS-5584

    PI3K inhibitor.

    ≥98%
  • S0501

    SB-939

    HDAC inhibitor.

    ≥98%
  • N2400

    NG-52

    Purine, purvalenol A analog; CDK2, Cdc28p, Pho8...

    ≥98%
  • S1853

    Senegenin

    Found in Polygata tennifolia.

    ≥98%
  • T2817

    Theophylline

    Methylxanthine; PDE inhibitor, A1/2 adenosine a...

    ≥98%
  • P4780

    Plumbagin

    Naphthoquinone found in Plumbago.

    ≥98%
  • D5746

    Dolasetron

    5-HT3 antagonist.

    ≥98%
  • C0252

    Canertinib Dihydrochloride

    EGFR inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only