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D,L-Tetrahydropalmatine

Product ID T1678
Cas No. 10097-84-4
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $93.70 In stock
500 mg $344.20 In stock
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  • Product Info
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  • Description
  • Product Info
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Description

D,L-Tetrahydropalmatine is an alkaloid found in Corydalis and Stephania that exhibits analgesic, antinociceptive, anxiolytic, antidepressant, and anti-parasitic activities. This compound inhibits D1/2 receptors and may also inhibit L-type Ca2+ channels and some K+ channels. D,L-Tetrahydropalmatine decreases anxiety measures in the elevated plus maze and alters thresholds in assays of thermal, mechanical, and chemical pain. D,L-Tetrahydropalmatine also inhibits growth of Plasmodium.

Product Info

Cas No.

10097-84-4

Purity

≥98%

Formula

C21H25NO4

Formula Wt.

355.43

Chemical Name

5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H- dibenzo[a,g]quinolizine

IUPAC Name

(13aS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2, 1-b]isoquinoline

Synonym

Tetrahydropalmatine, Hynndarin

Melting Point

148-149°C

Appearance

White crystalline

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T1678 MSDS PDF

Info Sheet

T1678 Info Sheet PDF

References

Baghdikian B, Mahiou-Leddet V, Bory S, et al. New antiplasmodial alkaloids from Stephania rotunda. J Ethnopharmacol. 2013 Jan 9;145(1):381-5. PMID: 23127648.

Cao FL, Shang GW, Wang Y, et al. Antinociceptive effects of intragastric DL-tetrahydropalmatine on visceral and somatic persistent nociception and pain hypersensitivity in rats. Pharmacol Biochem Behav. 2011 Nov;100(1):199-204. PMID: 21889526.

Henkes H, Franz M, Kendall O, et al. Evaluation of the anxiolytic properties of tetrahydropalmatine, a Corydalis yanhusuo compound, in the male Sprague-Dawley rat. AANA J. 2011 Aug;79(4 Suppl):S75-80. PMID: 22403971.

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