• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Dorsomorphin Dihydrochloride

Dorsomorphin Dihydrochloride

Product ID D582705
Cas No. 1219168-18-9
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $89.30 In stock
10 mg $152.30 In stock
25 mg $304.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Water soluble form of dorsomorphin (D582703), a selective and potent inhibitor of bone morphogenetic protein (BMP) through the receptors ALK2, ALK3, and ALK6. Inhibits AMPK, inducing autophagy in cancer cells. Shown to promote functional myogenesis along with LDN-193189.

Product Info

Cas No.

1219168-18-9

Purity

≥98%

Formula

C24H27Cl2N5O

Formula Wt.

472.41

IUPAC Name

6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine;dihydrochloride

Synonym

Dorsomorphin 2HCl; BML-275; BML-275 2HCl; Compound C; AK175513; 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine;dihydrochloride

Solubility

Water (100 mM), DMSO (20 mM).

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

D582705 MSDS PDF

Info Sheet

D582705 Info Sheet PDF

References

Yu P., Hong C., et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 34(1):33-41 (2008). PMID: 18026094.

Vucicevic L., Misirkic M., et al. Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway. Autophagy. 7(1):40-50 (2011). PMID: 20980833.

Horbelt D., Boergermann J., et al. Small molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation. J Biol Chem. 290(6):3390-404 (2015). PMID: 25368322.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • H5748

    D,L-Homocysteine Thiolactone Hydrochloride

    Heterocyclic derivative of cysteine, alters pro...

    ≥99%
  • F441026

    Flavopiridol Hydrochloride

    Semisynthetic flavone that acts as an inhibitor...

    ≥98%
  • S6247

    Splitomicin

    SIRT1/2 inhibitor.

    ≥98%
  • S1843

    L-Selectin

    Endogenous adhesion molecule, binds PKC, calmod...

    ≥95%
  • C9876

    CYT-387

    JAK2 inhibitor.

    ≥98%
  • P0008

    Pituitary Adenylate Cyclase-activating Peptide (6-38), human/sheep/rat

    Endogenous peptide, involved in paracrine and a...

    ≥95%
  • B465806

    BLU-667

    RET inhibitor.

    ≥98%
  • B1898

    Bezafibrate

    Fibrate; PPARα agonist.

    ≥98%
  • G1749

    Gemfibrozil

    Fibrate; PPARα agonist, enoyl-CoA reductase in...

    ≥98%
  • O783743

    OTSSP167 Hydrochloride

    MELK inhibitor.

    ≥98%
  • R5894

    Roxatidine Acetate Hydrochloride

    Histamine H2 antagonist.

    ≥98%
  • P1845

    Pelitinib

    EGFR inhibitor.

    ≥98%
  • C2965

    Chromium Picolinate

    Used to prevent chromium deficiency and to decr...

    ≥98%
  • S6168

    Spirapril Hydrochloride

    ACE inhibitor.

    ≥98%
  • A7657

    Atosiban Acetate

    Peptide, alters uterine contractility; V1/2 and...

    ≥95%
  • P2859

    Phosphate Acceptor Peptide

    PKC and S6 kinase substrate.

    ≥95%
  • A4497

    Alyssin Sulfone

    Naturally sourced ITC, sulfonyl analog of sulfo...

    ≥97%
  • A600002

    AP-26113

    Pan inhibitor of ALK.

    ≥98%
  • A4534

    Aliskiren Hemifumarate

    Renin inhibitor.

    ≥98%
  • I7357

    Isorhamnetin

    Flavonol found in Tagetes.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only