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Retinyl Palmitate

Retinyl Palmitate

Product ID R1879
Cas No. 79-81-2
Purity ≥1.70 MIU/g, bio assay
Product Unit SizeCostQuantityStock
5 g $52.00 In stock
25 g $75.10 In stock
100 g $145.10 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Retinyl palmitate is the ester of retinol and palmitic acid; it exhibits anti-metastatic and antioxidative activities. Retinyl palmitate is commercially used as a vitamin A supplement but it does not directly activate retinoic acid receptors (RARs) like other forms of vitamin A. In animal models of colon cancer, retinyl palmitate decreases cancer metastasis. In cellular models, this compound prevents oxidation of LDL. Retinyl palmitate displays both mutagenic as well as anticancer activities in various models; in one model, it induces DNA damage under UV light, and in another model it inhibits the proliferation of cancer cells.

This compound is packaged as a water-dispersable solid in a gelatin base; it has > 1% BHA,BHT, & α-Tocopherol added as preservatives. Retinyl palmitate is not as stable as retinyl acetate in pure form. 250,000 USP units per gram.

Product Info

Cas No.

79-81-2

Purity

≥1.70 MIU/g, bio assay

Formula

C36H60O2

Formula Wt.

524.86

IUPAC Name

[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4, 6,8-tetraenyl] hexadecanoate

Synonym

Vitamin A palmitate, Retinyl hexadecanoate, Aquasol A

Melting Point

28°C

Solubility

Insoluble in water. Soluble in chloroform, ether, edible oils. Slightly soluble in alcohol.

Appearance

Yellow waxy solid/oily liquid

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

R1879 MSDS PDF

Info Sheet

R1879 Info Sheet PDF

References

Park EY, Pinali D, Lindley K, et al. Hepatic vitamin A preloading reduces colorectal cancer metastatic multiplicity in a mouse xenograft model. Nutr Cancer. 2012;64(5):732-40. PMID: 22642873.

Mei N, Xia Q, Chen L, et al. Photomutagenicity of retinyl palmitate by ultraviolet a irradiation in mouse lymphoma cells. Toxicol Sci. 2005 Nov;88(1):142-9. PMID: 16107546.

Maziere S, Cassand P, Narbonne JF, et al. Vitamin A and apoptosis in colonic tumor cells. Int J Vitam Nutr Res. 1997;67(4):237-41. PMID: 9285252.

Livrea MA, Tesoriere L, Bongiorno A, et al. Contribution of vitamin A to the oxidation resistance of human low density lipoproteins. Free Radic Biol Med. 1995 Mar;18(3):401-9. PMID: 9101230.

Custom Order

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