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Emtricitabine

Emtricitabine

Product ID E5178
Cas No. 143491-57-0
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $63.00 In stock
10 mg $78.80 In stock
25 mg $99.80 In stock
50 mg $157.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Emtricitabine is a cytidine nucleoside analog reverse transcriptase inhibitor (NRTI) that is clinically used to treat HIV infection. This antiviral also displays some efficacy in the treatment of hepatitis B infection. Emtricitabine is typically co-administered with other antiretrovirals; it also inhibits telomerase activity in vitro.

Product Info

Cas No.

143491-57-0

Purity

≥98%

Formula

C8H10FN3O3S

Formula Wt.

247.25

IUPAC Name

4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

Solubility

DMSO ≥ 50 mg/ml, ethanol ≥ 17 mg/ml, Water 112 mg/ml. The log P for emtricitabine is -0.43 and the pKa is 2.65.

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

E5178 MSDS PDF

Info Sheet

E5178 Info Sheet PDF

Brochures

Antivirals Booklet

References

Kulkarni R, Hluhanich R, McColl DM, et al. The combined anti-HIV-1 activities of emtricitabine and tenofovir plus the integrase inhibitor elvitegravir or raltegravir show high levels of synergy in vitro. Antimicrob Agents Chemother. 2014 Oct;58(10):6145-50. PMID: 25092710.

Arribas JR, Eron J. Advances in antiretroviral therapy. Curr Opin HIV AIDS. 2013 Jul;8(4):341-9. PMID: 23666392.

Leeansyah E, Cameron PU, Solomon A, et al. Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging. J Infect Dis. 2013 Apr;207(7):1157-65. PMID: 23303810.

Custom Order

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