• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Estradiol

Estradiol

Product ID E7376
Cas No. 50-28-2
Purity ≥97%
Product Unit SizeCostQuantityStock
1 g $66.20 In stock
5 g $137.90 In stock
25 g $303.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Estradiol is an endogenous estrogenic steroid hormone commonly used in oral contraceptives and hormone replacement therapy (HRT). Estradiol regulates estrous and menstrual reproductive cycles, induces growth in reproductive organs, and increases secretion of luteinizing hormone (LH). Estradiol inhibits acetylcholine-induced vascular constriction in post-menopausal women and inhibits sperm apoptosis in vitro. Estradiol displays some additional anticancer potential, inhibiting growth and proliferation of prostate cancer cells. Estradiol also exhibits antioxidative benefit, inhibiting oxidative stress-induced cell death and damage and inhibiting glutamate-induced neurotoxicity.

Product Info

Cas No.

50-28-2

Purity

≥97%

Formula

C18H24O2

Formula Wt.

272.38

Chemical Name

(17β)-Estra-1,3,5(10)-triene-3,17-diol

IUPAC Name

(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16, 17-decahydrocyclopenta[a]phenanthrene-3,17-diol

Synonym

Dimenformon, Estrace, Estraderm, Evorel, Macrodiol, Menorest, Profoliol B, Systen, Vagifem, Zumenon

Melting Point

173-179°C

Solubility

Soluble in alcohol (35 mg/mL), acetone, dioxane, and other organic solvent. Insoluble in water.

Appearance

White or almost white Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

E7376 MSDS PDF

Info Sheet

E7376 Info Sheet PDF

References

Pentikäinen V, Erkkilä K, Suomalainen L, et al. Estradiol acts as a germ cell survival factor in the human testis in vitro. J Clin Endocrinol Metab. 2000 May;85(5):2057-67. PMID: 10843196.

Behl C, Widmann M, Trapp T, et al. 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro. Biochem Biophys Res Commun. 1995 Nov 13;216(2):473-82. PMID: 7488136.

Collins P, Rosano GM, Sarrel PM, et al. 17 beta-Estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart disease. Circulation. 1995 Jul 1;92(1):24-30. PMID: 7788912.

Carruba G, Pfeffer U, Fecarotta E, et al. Estradiol inhibits growth of hormone-nonresponsive PC3 human prostate cancer cells. Cancer Res. 1994 Mar 1;54(5):1190-3. PMID: 8118804.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T174441

    Telacebec

    Anti-tuberculosis

    ≥98%
  • F3207

    Fibronectin CS-1 Peptide

    Peptide; α4β1 integrin activator.

    ≥95%
  • A9813

    AZD-8931

    Inhibitor of EGFR, HER2, and HER3.

    ≥98%
  • S1059

    Scopolamine Hydrobromide Trihydrate

    Tropane alkaloid found in Solanaceae plants; M1...

    ≥98%
  • D183745

    Destruxin B

    Cyclic depsipeptide is a secondary metabolite i...

    ≥96%
  • O6805

    Orbifloxacin

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥99%
  • A5037

    Amiodarone Hydrochloride

    Voltage-gated Na+, Ca2+, K+ channel blocker, α...

    ≥98%
  • C4417

    Clemizole

    TRPC5 activator, NS4B and histamine H1 inhibito...

    ≥98%
  • P2922

    Phenylhexyl Isothiocyanate

    ITC found in cruciferous vegetables; HDAC inhib...

    ≥98%
  • A6368

    Aprepitant

    NK1 antagonist.

    ≥98%
  • G1749

    Gemfibrozil

    Fibrate; PPARα agonist, enoyl-CoA reductase in...

    ≥98%
  • M3344

    Milrinone

    PDE3 inhibitor.

    ≥98%
  • E9201

    EX-527

    SIRT1 inhibitor.

    ≥99%
  • C2816

    Cheirolin

    Naturally produced ITC, sulfonyl analog of sulf...

    ≥97%
  • L0226

    Lagochiline

    Diterpene alkaloid found in Lagochilus.

    ≥98%
  • P1622

    Pefloxacin Methanesulfonate Dihydrate

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • D1629

    Dehydroepiandrosterone

    Endogenous steroid hormone; ERβ, NMDA, σ1 ago...

    ≥98%
  • O9234

    Oxiconazole Nitrate

    Imidazole; 14-α demethylase inhibitor.

    ≥98%
  • S8146

    Sulindac Sulfone

    NSAID; COX-1/2 and PDE inhibitor.

    ≥98%
  • N8760

    NVP-TAE684

    ALK, c-Fes, LRRK2 inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only