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This peptide is an FMRFamide peptide found in Lymnaea with the sequence GDPFLRF. FMRF is a cardiostimulatory neuropeptide involved in reproductive behavior control. FMRF increases the magnitude of delayed rectifier K+ current (I(K)) in olfactory neurons and inhibits the exchange of Na+ and Ca2+.
| Cas No. | 98495-35-3 |
|---|---|
| Purity | ≥98% |
| Formula | C44H62N11O10 |
| Formula Wt. | 904.03 |
| Solubility | Soluble in water. |
| Appearance | White to off white powder |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Di Cristo C. Nervous control of reproduction in Octopus vulgaris: a new model. Invert Neurosci. 2013 Jun;13(1):27-34. PMID: 23558706.
Ringstad N, Horvitz HR. FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans. Nat Neurosci. 2008 Oct;11(10):1168-76. PMID: 18806786.
Ni MM, Luo Y, Liu J, et al. FMRFamide modulates outward potassium currents in mouse olfactory sensory neurons. Clin Exp Pharmacol Physiol. 2008 May;35(5-6):563-7. PMID: 18067588.
Skingsley DR, Bright K, Santama N, et al. A molecularly defined cardiorespiratory interneuron expressing SDPFLRFamide/GDPFLRFamide in the snail Lymnaea: monosynaptic connections and pharmacology. J Neurophysiol. 1993 Mar;69(3):915-27. PMID: 8096540.
Ebberink RH, Price DA, van Loenhout H, et al. The brain of Lymnaea contains a family of FMRFamide-like peptides. Peptides. 1987 May-Jun;8(3):515-22. PMID: 3658814.