• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Foscarnet Sodium Hydrate

Foscarnet Sodium Hydrate

Product ID F5873
Cas No. 34156-56-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $126.50 In stock
5 g $493.00 In stock
10 g $845.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Foscarnet is an antiviral compound that inhibits reverse transcriptase of HIV-1 and DNA polymerase of other viruses, including CMV and HSV. Inhibition of these enzymes prevents DNA synthesis and viral replication. Foscarnet chelates with metal ions and also mimics the pyrophosphate leaving group in DNA polymerase, inducing a closed/un-translocated conformational state. Additionally, foscarnet inhibits type II inorganic phosphate (Pi) transporters in smooth muscle cells, inhibiting Ca2+ deposition and vascular calcification.

Product Info

Cas No.

34156-56-4

Purity

≥98%

Formula

CNa3O5P • 6H2O

Formula Wt.

300.04

Chemical Name

Foscarnet Sodium Hexahydrate

IUPAC Name

trisodium;phosphonatoformate

Synonym

Phosphonoformic acid sodium salt hydrate; Trisodium phosphonoformate, Foscavir

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F5873 MSDS PDF

Info Sheet

F5873 Info Sheet PDF

References

Zahn KE, Tchesnokov EP, Götte M, et al. Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase. J Biol Chem. 2011 Jul 15;286(28):25246-55. PMID: 21566148.

Villa-Bellosta R, Sorribas V. Phosphonoformic acid prevents vascular smooth muscle cell calcification by inhibiting calcium-phosphate deposition. Arterioscler Thromb Vasc Biol. 2009 May;29(5):761-6. PMID: 19213941.

Marchand B, Tchesnokov EP, Götte M. The pyrophosphate analogue foscarnet traps the pre-translocational state of HIV-1 reverse transcriptase in a Brownian ratchet model of polymerase translocation. J Biol Chem. 2007 Feb 2;282(5):3337-46. PMID: 17145704.

Morfin F, Thouvenot D. Herpes simplex virus resistance to antiviral drugs. J Clin Virol. 2003 Jan;26(1):29-37. PMID: 12589832.

Hardy WD. Foscarnet treatment of acyclovir-resistant herpes simplex virus infection in patients with acquired immunodeficiency syndrome: preliminary results of a controlled, randomized, regimen-comparative trial. Am J Med. 1992 Feb 14;92(2A):30S-35S. PMID: 1531285.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • Z324098

    Ziconotide

    Non-opioid analgesic.

    ≥95%
  • P1849

    Pemetrexed Disodium

    Thymidylate synthase inhibitor, potential SHMT,...

    ≥98%
  • S5868

    Sorafenib

    c-Raf, Ret, VEGFR2 inhibitor, potential STAT3/5...

    ≥98%
  • T1014

    7-TES-Paclitaxel

    Synthesis impurity

    ≥95%
  • F3473

    Fisetin

    Flavonoid found in various plant sources; matri...

    ≥97%
  • A0402

    Abacavir Sulfate

    Nucleoside (guanosine) analog; RT, guanylyl cyc...

    ≥98%
  • D0353

    Danofloxacin Mesylate

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • F4502

    Flavokawain A

    Chalcone kavalactone found in Piper methysticum...

    ≥98%
  • G733404

    GSK3685032

    Reversible DNMT1-selective inhibitor

    ≥98%
  • M4452

    MLN2480

    Raf inhibitor.

    ≥98%
  • P1853

    Penicillin V Potassium

    Hydrophobic β-lactam; penicillin binding prote...

    ≥98%
  • D760022

    DT-2216

    BCL-XL specific degrader

    ≥98%
  • N3378

    S-Nitrosoglutathione

    NO donor.

    ≥95%
  • A7034

    Aripiprazole

    D2 and 5-HT1A partial agonist, 5-HT2C/6/7 antag...

    ≥98%
  • A0967

    Adrenocorticotropic Hormone (1-17), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • O7992

    OTX-015

    BRD2/3/4 inhibitor.

    ≥98%
  • P005095

    N-Debenzoylpaclitaxel

    Paclitaxel derivative

    ≥95%
  • D582705

    Dorsomorphin Dihydrochloride

    Inhibitor of ALK2, ALK3, ALK6, and AMPK.

    ≥98%
  • T7034

    Trimethoprim

    Dihydrofolate reductase inhibitor.

    ≥98%
  • B1668

    Berteroin

    Thio sulforaphane analog, ITC.

    ≥97%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only