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Rocuronium Bromide

Product ID R5611
Cas No. 119302-91-9
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $64.90 In stock
25 mg $111.30 In stock
100 mg $279.60 In stock
250 mg $538.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Rocuronium is an aminosteroid that exhibits anesthetic activity, inducing relaxation of skeletal muscle. Rocuronium is a non-depolarizing neuromuscular junction (NMJ) blocker that inhibits post-synaptic nicotinic acetylcholine receptors (nAChRs); it also inhibits M2/3 muscarinic acetylcholine receptors (mAChRs). Rocuronium has a rapid onset and can be administered with a specific antagonist that terminates its action.

Product Info

Cas No.

119302-91-9

Purity

≥98%

Formula

C32H53BrN2O4

Formula Wt.

609.68

IUPAC Name

[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-hydroxy-10, 13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enylpyrrolidin-1-ium-1-yl)-2, 3,4,5,6,7,8,9,11,12,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate;bromide

Melting Point

162-164°C

Solubility

Soluble in water, ethanol, DMSO, chloroform, methanol.

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

R5611 MSDS PDF

Info Sheet

R5611 Info Sheet PDF

References

Pape A, Kertscho H, Stein P, et al. Neuromuscular blockade with rocuronium bromide increases the tolerance of acute normovolemic anemia in anesthetized pigs. Eur Surg Res. 2012;48(1):16-25. PMID: 22189343.

Bowman WC. Neuromuscular block. Br J Pharmacol. 2006 Jan;147 Suppl 1:S277-86. PMID: 16402115.

Hou VY, Hirshman CA, Emala CW. Neuromuscular relaxants as antagonists for M2 and M3 muscarinic receptors. Anesthesiology. 1998 Mar;88(3):744-50. PMID: 9523819.

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