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Glucagon-like Peptide I (7-37)

Glucagon-like Peptide I (7-37)

Product ID G4482
Cas No. 106612-94-6
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $265.90 In stock
1 mg $470.20 In stock
2.5 mg $953.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Glucagon-like peptide 1 (GLP-1) is an endogenous peptide hormone that binds GLP-1 receptors, increasing cAMP and insulin secretion. GLP-1 primarily exhibits anorexigenic, anti-diabetic, and gastrointestinal modulatory activities. GLP-1 decreases food intake and glucagon levels in animal models and also slows gastric emptying. In subjects with type 2 diabetes, the response of GLP-1 to glucose is impaired and subjects show abnormally low levels of GLPs.

Product Info

Cas No.

106612-94-6

Purity

≥95%

Formula

C151H228N40O47

Formula Wt.

3355.67

Synonym

Insulinotropin, Tglp-1, GLP-1, Preproglucagon (78-108)

Solubility

Soluble in water (1 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G4482 MSDS PDF

Info Sheet

G4482 Info Sheet PDF

References

Kim S, Wan Kim S, Bae YH. Synthesis, bioactivity and specificity of glucagon-like peptide-1 (7-37)/polymer conjugate to isolated rat islets. Biomaterials. 2005 Jun;26(17):3597-606. PMID: 15621250.

Vahl TP, Paty BW, Fuller BD, et al. Effects of GLP-1-(7-36)NH2, GLP-1-(7-37), and GLP-1- (9-36)NH2 on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans. J Clin Endocrinol Metab. 2003 Apr;88(4):1772-9. PMID: 12679472.

Mannucci E, Ognibene A, Cremasco F, et al. Glucagon-like peptide (GLP)-1 and leptin concentrations in obese patients with Type 2 diabetes mellitus. Diabet Med. 2000 Oct;17(10):713-9. PMID: 11110504.

Nauck MA. Glucagon-like peptide 1 (GLP-1): a potent gut hormone with a possible therapeutic perspective. Acta Diabetol. 1998 Oct;35(3):117-29. PMID: 9840447.

Custom Order

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