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Venlafaxine Hydrochloride

Product ID V1854
Cas No. 99300-78-4
Purity ≥98%
Product Unit SizeCostQuantityStock
500 mg $100.90 In stock
1 g $163.60 In stock
5 g $450.00 In stock
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  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
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  • Downloads
  • References
  • Custom Order

Description

Venlafaxine is an inhibitor of the serotonin transporter (SERT), norepinephrine transporter (NET), and monoamine oxidase (MAO). Venlafaxine exhibits antidepressant, analgesic, and neuroprotective activities. Venlafaxine decreases pain in animal models of diabetic neuropathy and improves cognitive performance and decreases oxidative stress parameters in 3-NP-treated animal models of Huntington’s disease.

Product Info

Cas No.

99300-78-4

Purity

≥98%

Formula

C17H27NO2 • HCl

Formula Wt.

313.87

Chemical Name

1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)- cyclohexanol hydrochloride

IUPAC Name

1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol; hydrochloride

Synonym

Effexor, HSDB 6699, Wy 45030

Melting Point

215-217°C

Solubility

Soluble in water.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

V1854 MSDS PDF

Info Sheet

V1854 Info Sheet PDF

References

Vidal R, Diaz A, Pazos A, et al. Region-specific regulation of 5-HT1B receptors in the rat brain by chronic venlafaxine treatment. Psychopharmacology (Berl). 2013 Sep;229(1):177-85. PMID: 23609771.

Cegielska-Perun K, Bujalska-Zadrożny M, Tatarkiewicz J, et al. Venlafaxine and neuropathic pain. Pharmacology. 2013;91(1-2):69-76. PMID: 23183148.

Fisar Z, Hroudová J, Raboch J. Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers. Neuro Endocrinol Lett. 2010;31(5):645-56. PMID: 21200377.

Kumar P, Kalonia H, Kumar A. Nitric oxide mechanism in the protective effect of antidepressants against 3-nitropropionic acid-induced cognitive deficit, glutathione and mitochondrial alterations in animal model of Huntington's disease. Behav Pharmacol. 2010 May;21(3):217-30. PMID: 20480544.

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