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GSK-343

GSK-343

Product ID G7442
Cas No. 1346704-33-3
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $59.00 In stock
5 mg $123.00 Please Inquire
10 mg $214.00 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

GSK-343 is an inhibitor of enhancer of zeste homolog 2 (EZH2) histone methyltransferase (HMT). GSK-343 exhibits anticancer activity, inhibiting cell invasion and cell growth in epithelial ovarian cancer cells.

Product Info

Cas No.

1346704-33-3

Purity

≥98%

Formula

C31H39N7O2

Formula Wt.

541.69

IUPAC Name

N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[2-(4-methylpiperazin-1-yl)pyridin-4-yl]-1-propan-2-ylindazole-4-carboxamide

Solubility

Ethanol (2 mg/ml), DMSO (15 mg/ml), DMF (25 mg/ml)

Appearance

Brown or Gray Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

G7442 MSDS PDF

Info Sheet

G7442 Info Sheet PDF

Brochures

Epigenetic Modifiers Booklet

References

Amatangelo MD, Garipov A, Li H, et al. Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition. Cell Cycle. 2013 Jul 1;12(13):2113-9. PMID: 23759589.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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