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H89

H89

Product ID H0003
Cas No. 127243-85-0
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $45.50 In stock
5 mg $129.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

H89 is an inhibitor of PKA that is used to study the effects of PKA signaling in research models. H89 may also inhibit Rho-associated protein kinase (ROCK), S6K1, MSK1, PKBa, and MAPKAP-K1b.

Product Info

Cas No.

127243-85-0

Purity

≥98%

Formula

C20H20BrN3O2S

Formula Wt.

446.36

Chemical Name

N-(2-[P-Bromocinnamylamino]-ethyl)-5-isoquinolinesulfonmide

IUPAC Name

N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5- sulfonamide;dihydrochloride

Synonym

H-89

Melting Point

141-143°C

Solubility

Soluble in DMSO or ethanol:water (1:1).

Appearance

White powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

H0003 MSDS PDF

Info Sheet

H0003 Info Sheet PDF

References

Choi S, Kim MY, Joo KY, et al. Modafinil inhibits K(Ca)3.1 currents and muscle contraction via a cAMP-dependent mechanism. Pharmacol Res. 2012 Jul;66(1):51-9. PMID: 22414869.

Rogers RC, Hermann GE. Tumor necrosis factor activation of vagal afferent terminal calcium is blocked by cannabinoids. J Neurosci. 2012 Apr 11;32(15):5237-41. PMID: 22496569.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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