[His18]-Amylin, rat

Name: [His18]-Amylin, rat
SKU: A4850
Availability: InStock

Product ID A4850

Cas No.

Purity ≥95%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Amylin is also known as islet amyloid precursor peptide (IAPP) and is co-secreted with insulin from pancreatic β-cells. Amylin is an endogenous peptide hormone that exhibits gastrointestinal motility modulating activity, decreasing gastric emptying and suppressing gastric acid secretion; these actions slow food intake, preventing blood glucose spikes after eating and decreasing insulin demand. Misguided IAPP processing plays a significant role in the development of diabetes mellitus type 2. Like calcitonin, IAPP inhibits osteoclast activity and Ca2+ reabsorption in bones. This peptide binds to calcitonin-RAMP complexes.

Product Info

Purity	≥95%
Formula	C₁₆₇H₂₆₇N₅₁O₅₃S₂
Formula Wt.	3901.43
Synonym	IAPP, islet amyloid precursor peptide
Solubility	Soluble in water.
Appearance	White to off white powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	A4850 MSDS PDF
Info Sheet	A4850 Info Sheet PDF

References

Paulsson JF, Westermark GT. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation. Diabetes. 2005 Jul;54(7):2117-25. PMID: 15983213.

Ratner RE, Dickey R, Fineman M, et al. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. Diabet Med. 2004 Nov;21(11):1204-12. PMID: 15498087.

Pittner RA, Albrandt K, Beaumont K, et al. Molecular physiology of amylin. J Cell Biochem. 1994;55 Suppl:19-28. PMID: 7929615.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Comments
This field is for validation purposes and should be left unchanged.

[His18]-Amylin, rat

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Sucralfate

LY-450139

4′-Demethylepipodophyllotoxin

Mifepristone

L-(+)-Alliin

Raltegravir

Apararenone

Mechlorethamine Hydrochloride

Penciclovir

Filipin III

R,S-Sulforaphane, Research Grade

NU-2058

4-tert-Butyl-5-Methoxycatechol

Fumonisin B3

JTE907

Cyclosporin H

HU 308

Aristolochic Acid C

Lumiracoxib

TG100-115

Footer