• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Hyperforin Dicyclohexylammonium

Hyperforin Dicyclohexylammonium

Product ID H9863
Cas No. 238074-03-8
Purity ≥97%
Product Unit SizeCostQuantityStock
500 µg $306.20 In stock
1 mg $501.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Hyperforin DCHA is a stable salt form of hyperforin, a compound found in Hypericum perforatum (St. John’s Wort). Hyperforin DCHA exhibits anticancer, anti-inflammatory, and antidepressant activities. In chronic myelogenous leukemia (CML) cells, hyperforin DCHA disrupts the mitochondrial membrane potential, increases release of cytochrome c, activates caspases 3, 8, and 9, and induces cleavage of poly(ADP)-ribose polymerase (PARP), resulting in G1 phase cell cycle arrest and apoptosis. In astrocytoma cells, hyperforin DCHA prevents LPS- and substance P-induced release of IL-6. In animal models, this compound prevents croton oil-induced edema. Additionally, hyperforin DCHA decreases immobility time in animals undergoing the forced swim test.

Product Info

Cas No.

238074-03-8

Purity

≥97%

Formula

C35H52O4 • C12H23N

Formula Wt.

718.10

IUPAC Name

N-cyclohexylcyclohexanamine;(1R,5R,6R,7S)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione

Synonym

Hyperforin DCHA

Solubility

Soluble in DMSO (≥10 mg/ml), methanol, and 100% ethanol

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

H9863 MSDS PDF

Info Sheet

H9863 Info Sheet PDF

References

Liu JY, Liu Z, Wang DM, et al. Induction of apoptosis in K562 cells by dicyclohexylammonium salt of hyperforin through a mitochondrial-related pathway. Chem Biol Interact. 2011 Apr 25;190(2-3):91-101. PMID: 21376709.

Sosa S, Pace R, Bornancin A, et al. Topical anti-inflammatory activity of extracts and compounds from Hypericum perforatum L. J Pharm Pharmacol. 2007 May;59(5):703-9. PMID: 17524236.

Gobbi M, Moia M, Funicello M, et al. In vitro effects of the dicyclohexylammonium salt of hyperforin on interleukin-6 release in different experimental models. Planta Med. 2004 Jul;70(7):680-2. PMID: 15303261.

Cervo L, Rozio M, Ekalle-Soppo CB, et al. Role of hyperforin in the antidepressant-like activity of Hypericum perforatum extracts. Psychopharmacology (Berl). 2002 Dec;164(4):423-8. PMID: 12457273.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A6982

    Artesunate

    Sesquiterpene lactone derived from Artemesia.

    ≥98%
  • C5655

    α-Conotoxin GI

    Peptide toxin found in Conus snails; nAChR inhi...

    ≥95%
  • S8248

    Sulfamethoxazole

    Sulfonamide; PABA inhibitor.

    ≥98%
  • D3362

    Dipyridamole

    PDE and adenosine deaminase inhibitor.

    ≥98%
  • G1209

    GDC-0980

    PI3K and mTOR inhibitor.

    ≥98%
  • F4503

    Flavokawain B

    Chalcone kavalactone that suppresses inflammati...

    ≥97%
  • E5211

    Endomorphin-2

    Endogenous opioid peptide; μOR agonist.

    ≥95%
  • R327201

    Rifapentine

    Antibiotic

    ≥97%
  • A1218

    Adefovir Dipivoxil

    Acyclic nucleotide (adenosine) analog, adefovir...

    ≥98%
  • Y0002

    Y-320

    Phenylpyrazoleanilide; IL-17 production inhibit...

    ≥98%
  • B0026

    Bafilomycin B1

    Macrolide; vacuolar H+-ATPase inhibitor.

    ≥97%
  • K0053

    Kanamycin A Monosulfate

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • E537333

    Enniatin A1

    Mycotoxin contaminant found in cereal grains.

    ≥98%
  • D8145

    Duloxetine Hydrochloride

    SERT and NET inhibitor, Nav1.7 Na+ channel bloc...

    ≥99%
  • B1640

    Benzydamine Hydrochloride

    NSAID; PG synthetase inhibitor.

    ≥98%
  • C0021

    Cafestol Acetate

    Diterpene found in brewed, unfiltered coffee; F...

    ≥98%
  • E7433

    Etidronate Disodium

    Bisphosphonate, chelating agent.

    ≥98%
  • P2002

    PF-04691502 Dihydrate

    PI3K and mTOR inhibitor.

    ≥98%
  • G6803

    Granuliberin R

    Antimicrobial peptide found in amphibians.

    ≥95%
  • O938567

    4-epi-6-Oxodocetaxel

    Docetaxel impurity

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only