Ipriflavone is a synthetic isoflavone that exhibits anti-osteoporotic, anti-resorptive, and cytoprotective activities. In animal models of low Ca2+ diet, ipriflavone decreases bone resorption and increases bone density and volume. In vitro, this compound protects against cyclophosphamide-induced DNA damage.
| Cas No. | 35212-22-7 |
|---|---|
| Purity | ≥98% |
| Formula | C18H16O3 |
| Formula Wt. | 280.32 |
| Chemical Name | 7-(1-Methylethoxy)-3-phenyl-4H-1-benzopyran-4-one |
| IUPAC Name | 3-phenyl-7-propan-2-yloxychromen-4-one |
| Synonym | Iprosten, Osten, Osteofix, Yambolap |
| Melting Point | 115-117°C |
| Solubility | Poor solubility in water. Soluble in DMSO. |
| Appearance | White Crystal Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Lv WT, Yang YH, Ma LQ, et al. Ipriflavone reverses the adverse effects of a low-calcium diet on the histology of the tibia in caged layers. Br Poult Sci. 2014;55(2):207-14. PMID: 24404906.
Delarmelina JM, Dutra JC, Batitucci Mdo C. Antimutagenic activity of ipriflavone against the DNA-damage induced by cyclophosphamide in mice. Food Chem Toxicol. 2014 Mar;65:140-6. PMID: 24389340.
