Description
This peptide (MRFFV) confers resistance to ketolide antibiotics, preventing antibiotic binding of bacterial ribosomes and allowing the continuation of protein synthesis.
| Product Unit Size | Cost | Quantity | Stock |
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This peptide (MRFFV) confers resistance to ketolide antibiotics, preventing antibiotic binding of bacterial ribosomes and allowing the continuation of protein synthesis.
| Purity | ≥98% |
|---|---|
| Formula | C34H50N8O6S |
| Formula Wt. | 698.88 |
| Solubility | Soluble in water. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
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Verdier L, Gharbi-Benarous J, Bertho G, et al. Antibiotic resistance peptides: interaction of peptides conferring macrolide and ketolide resistance with Staphylococcus aureus ribosomes: conformation of bound peptides as determined by transferred NOE experiments. Biochemistry. 2002 Apr 2;41(13):4218-29. PMID: 11914067.
Tripathi S, Kloss PS, Mankin AS. Ketolide resistance conferred by short peptides. J Biol Chem. 1998 Aug 7;273(32):20073-7. PMID: 9685347.
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