Description
Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities. In vitro, this compound inhibits cell growth and induces apoptosis and in vivo, it decreases tumor growth.
Product Unit Size | Cost | Quantity | Stock |
---|
Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities. In vitro, this compound inhibits cell growth and induces apoptosis and in vivo, it decreases tumor growth.
Cas No. | 454453-49-7 |
---|---|
Purity | ≥98% |
Formula | C14H9F4N5O4S |
Formula Wt. | 419.31 |
Chemical Name | 2-[2,6-Dinitro-4-(trifluoromethyl)phenyl]-N-(4-fluorophenyl)hydrazinecarbothioamide |
IUPAC Name | 2-[2,6-Dinitro-4-(trifluoromethyl)phenyl]-N-(4-fluorophenyl)hydrazinecarbothioamide |
Synonym | 2-[2,6-Dinitro-4-(trifluoromethyl)phenyl]-N-(4-fluorophenyl)hydrazinecarbothioamide |
Solubility | DMSO: 15 mg/mL |
Appearance | Light yellow solid |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Shima F, Yoshikawa Y, Ye M, et al. In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8182-7. PMID: 23630290.
Shima F, Yoshikawa Y, Matsumoto S, et al. Discovery of small-molecule Ras inhibitors that display antitumor activity by interfering with Ras·GTP-effector interaction. Enzymes. 2013;34 Pt. B:1-23. PMID: 25034098.
Isothiocyanate found in cruciferous vegetables,...
Sesquiterpene lactone found in Artemisia (wormw...
Orexin 2 receptor antagonist
Selective inhibitor of LRRK2.
Aminothiol, CoA component; ulcer inducer.
Oxazoline; glucocorticoid agonist.
Synthetic derivative of selenocyanate.
CID-797718 analog; potential PKD1 binding agent...
Non-selective HDAC inhibitor.
BK K+ channel and L-type Ca2+ channel blocker.<...
Cephalotaxine alkaloid originally found in Ceph...
Mycotoxin produced by various fungi including t...
Sulfur analog of furan found in cooked meat pro...
Xanthine derivative; PDE inhibitor.
Pheniramine derivative; histamine H1 and mAChR ...
Rapamycin impurity
Triterpene found in species of Citrus; HIV-1 pr...
GRP analog, found in Bombina; bombesin and GRP ...
Diterpene found in coffee beans.
Nitrofuran, livestock antibiotic.