Description
KT5283 is an inhibitor of PKG and is used to measure PKG activity and downstream effects of PKG/cGMP signaling.
KT5283 is an inhibitor of PKG and is used to measure PKG activity and downstream effects of PKG/cGMP signaling.
| Cas No. | 126643-37-6 |
|---|---|
| Purity | ≥98% |
| Formula | C28H23N3O5 |
| Formula Wt. | 495.5 |
| IUPAC Name | methyl (15S,16R,18R)-16-methoxy-4,15-dimethyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate |
| Solubility | DMSO, Ethyl Acetate |
| Appearance | White Solid |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Salloum FN, Das A, Samidurai A, et al. Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide. Am J Physiol Heart Circ Physiol. 2012 Mar 15;302(6):H1347-54. PMID: 22268103.
Moreno H, Vega-Saenz de Miera E, Nadal MS, et al. Modulation of Kv3 potassium channels expressed in CHO cells by a nitric oxide-activated phosphatase. J Physiol. 2001 Feb 1;530(Pt 3):345-58. PMID: 11281123.
Xanthine derivative; adenosine antagonist, PDE ...
PDE and adenosine deaminase inhibitor.
Xanthine derivative; PDE inhibitor.
Selective 5-HT6 receptor antagonist
Cysteine protease inhibitor.
Cysteine adduct inducer, PARP-1 inhibitor.
Sterol cell membrane component found in yeast a...
p110δ PI3K inhibitor.
α-glucosidase inhibitor, potential GLP-1 agoni...
Endogenous bile acid; FXR agonist.
Phytoalexin, indole found in cruciferous vegeta...
GLP-1/GIP receptor co-agonist
USP1 inhibitor
Flavonol found in Tagetes.
JAK1/2 inhibitor.
Orexin 2 receptor antagonist
PDEδ inhibitor.
Flavone found in Scutellaria; prolyl oligopepti...
Furanolactone found in Citrus.
Broad-spectrum antiviral activity against SARS-...