Description
KT5283 is an inhibitor of PKG and is used to measure PKG activity and downstream effects of PKG/cGMP signaling.
KT5283 is an inhibitor of PKG and is used to measure PKG activity and downstream effects of PKG/cGMP signaling.
Cas No. | 126643-37-6 |
---|---|
Purity | ≥98% |
Formula | C28H23N3O5 |
Formula Wt. | 495.5 |
IUPAC Name | methyl (15S,16R,18R)-16-methoxy-4,15-dimethyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate |
Solubility | DMSO, Ethyl Acetate |
Appearance | White Solid |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Salloum FN, Das A, Samidurai A, et al. Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide. Am J Physiol Heart Circ Physiol. 2012 Mar 15;302(6):H1347-54. PMID: 22268103.
Moreno H, Vega-Saenz de Miera E, Nadal MS, et al. Modulation of Kv3 potassium channels expressed in CHO cells by a nitric oxide-activated phosphatase. J Physiol. 2001 Feb 1;530(Pt 3):345-58. PMID: 11281123.
Cannabinoid receptor 2 selective agonist.
Mast cell stabilizer; TRPV2 antagonist, PDGFR i...
Endogenous sterol component of animal cell memb...
NSAID; PG synthetase inhibitor.
NDRI inhibitor
Triazole; 14-α demethylase inhibitor, potentia...
Non-steroidal MRA
Vitamin A carboxylic acid; RAR agonist.
Neuropeptide found in Schistocera gregaria.
CDK1/2 inhibitor.
Inhibitor of Abl, c-Kit, and PDGFR.
Synthetic nitrile compound
Calcium channel blocker.
Steroidal alkaloid found in Fritillaria; TRPV1 ...
FIASMA, μOR agonist, potential HCN channel blo...
Benzophenanthridine alkaloid found in various p...
Nitrosourea, DNA alkylator.
Neuropeptide found in Locusta migratoria.
Flavonoid found in Rhus verniciflua and Butea m...
Naphthalene; indirect STAT1 agonist.