Description
KT5283 is an inhibitor of PKG and is used to measure PKG activity and downstream effects of PKG/cGMP signaling.
KT5283 is an inhibitor of PKG and is used to measure PKG activity and downstream effects of PKG/cGMP signaling.
Cas No. | 126643-37-6 |
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Purity | ≥98% |
Formula | C28H23N3O5 |
Formula Wt. | 495.5 |
IUPAC Name | methyl (15S,16R,18R)-16-methoxy-4,15-dimethyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate |
Solubility | DMSO, Ethyl Acetate |
Appearance | White Solid |
Store Temp | 4°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Salloum FN, Das A, Samidurai A, et al. Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide. Am J Physiol Heart Circ Physiol. 2012 Mar 15;302(6):H1347-54. PMID: 22268103.
Moreno H, Vega-Saenz de Miera E, Nadal MS, et al. Modulation of Kv3 potassium channels expressed in CHO cells by a nitric oxide-activated phosphatase. J Physiol. 2001 Feb 1;530(Pt 3):345-58. PMID: 11281123.
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