• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Levocetirizine Dihydrochloride

Levocetirizine Dihydrochloride

Product ID L1780
Cas No. 130018-87-0
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $79.10 In stock
5 g $164.00 In stock
25 g $631.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Levocetirizine ( (R)-Cetirizine dihydrochloride) is the L-isomer of cetirizine, a second-generation histamine H1 receptor antagonist. Levocetirizine exhibits anti-allergic, anti-inflammatory, and immunomodulatory activities. In animal models of allergic conjunctivitis, levocetirizine decreases levels of lipoxin A4, TNF-α, TGF-β, and antigen presenting cells (APCs) and increases levels of IL-10. Additionally, this compound increases levels of CD4+ CD25+ T cells and decreases levels of eosinophils, decreasing allergy symptoms in clinical settings.

Product Info

Cas No.

130018-87-0

Purity

≥98%

Formula

C21H25ClN2O3 • 2HCl

Formula Wt.

461.81

Chemical Name

Acetic acid, (2-(4-((R)-(4-chlorophenyl)phenylmethyl)-1- piperazinyl)ethoxy)- hydrochloride

IUPAC Name

2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid;dihydrochloride

Synonym

(−)-Cetirizine, Xusal, Xyzal, (R)-Cetirizine dihydrochloride

Melting Point

215-220°C

Appearance

White to off-white crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

L1780 MSDS PDF

Info Sheet

L1780 Info Sheet PDF

References

García-Zepeda S, Estrada-Muñiz E, Elizondo G, et al. Levocetirizine inhibits migration of immune cells to lymph nodes and induces treg cells in a murine type I allergic conjunctivitis model. Open Ophthalmol J. 2012;6:129-36. PMID: 23284599.

Mahmoud F, Arifhodzic N, Haines D, et al. Levocetirizine modulates lymphocyte activation in patients with allergic rhinitis. J Pharmacol Sci. 2008 Oct;108(2):149-56. PMID: 18946193.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A4845

    Amylin (8-37), rat

    Endogenous peptide hormone inolved in gastric e...

    ≥95%
  • T1978

    Tetrahydroberberine

    Isoquinoline alkaloid found in Corydalis; 5-HT1...

    ≥98%
  • T7031

    Triflumuron

    Insect growth regulator; chitin synthesis inhib...

    ≥98%
  • R5992

    Roxithromycin

    Macrolide; protein synthesis inhibitor.

    ≥96%
  • C1878

    Cetrimide

    Mixture of quaternary ammonium salts, cationic ...

    ≥98%
  • P6800

    Pravastatin Lactone

    Statin; HMG-CoA reductase inhibitor.

    ≥98%
  • T5608

    α-Tocotrienol

    Antioxidant, vitamin E derivative found in vege...

    ≥98%
  • C0278

    (+)-Catechin

    Flavanol originally found in Camilla (green tea...

    ≥99%
  • D5662

    Dopamine Hydrochloride

    Endogenous hormone neurotransmitter, involved i...

    ≥99%
  • T564091

    β-Tocopherol

    Vitamin E component

    ≥98%
  • A7618

    Atenolol

    β1-adrenergic antagonist.

    ≥98%
  • G4482

    Glucagon-like Peptide I (7-37)

    Endogenous peptide hormone, GLP-1 fragment, inv...

    ≥95%
  • T162053

    Tebipenem pivoxil

    Prodrug

    ≥99%
  • A4844

    Amylin (8-37), human

    Endogenous peptide hormone inolved in gastric e...

    ≥95%
  • L0528

    LBH-589

    HDAC1/2/3/11 inhibitor.

    ≥98%
  • A5070

    Angiotensin Acetate

    Peptide, derivative of AT I, cleavage product o...

    ≥95%
  • M3584

    Mivacurium

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • G3554

    Ginsenoside Rb3

    Triterpene saponin found in species of Panax.

    ≥98%
  • S3353

    Sinomenine Hydrochloride

    Alkaloid found in Sinomenium; acid-sensing ion ...

    ≥98%
  • H9802

    Hyaluronic Acid Sodium (7-10 kDA)

    Glycosaminoglycan

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only