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Lincomycin Hydrochloride Monohydrate

Lincomycin Hydrochloride Monohydrate

Product ID L3454
Cas No. 7179-49-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $75.10 In stock
5 g $315.40 In stock
25 g $826.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Lincomycin is a lincosamide antibiotic found in Streptomyces. Lincomycin exhibits antibacterial activity by binding the bacterial 50S ribosome subunit, inhibiting peptidyl transferase, and inducing dissociation of peptidyl-tRNA from the ribosome. Lincomycin also displays anti-parasitic/antimalarial activity against Plasmodium.

Product Info

Cas No.

7179-49-9

Purity

≥98%

Formula

C18H34N2O6S • HCl • H2O

Formula Wt.

461.01

Chemical Name

(2S-trans)-Methyl6,8-dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]-amino]-1-thio-D-erythro-α- D-galacto-octopyranoside hydrochloride monohydrate

IUPAC Name

(2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4, 5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4- propylpyrrolidine-2-carboxamide;hydrochloride

Synonym

Lincomycin hydrochloride monohydrate, Albiotic, Cillimycin, Lincomix

Melting Point

156-158°C

Solubility

Soluble in water (50mg/mL).

Appearance

White or almost white crystal Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

L3454 MSDS PDF

Info Sheet

L3454 Info Sheet PDF

References

Tenson T, Lovmar M, Ehrenberg M. The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. J Mol Biol. 2003 Jul 25;330(5):1005-14. PMID: 12860123.

Menninger JR. Mechanism of inhibition of protein synthesis by macrolide and lincosamide antibiotics. J Basic Clin Physiol Pharmacol. 1995;6(3-4):229-50. PMID: 8852269.

Custom Order

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