Description
Meropenem is a carbapenem β-lactam antibiotic that inhibits penicillin binding proteins, preventing cell wall synthesis. Meropenem exhibits antibacterial activity against Morganella, Enterobacter, Klebsiella, Mycobacterium, and Bacillus.
Meropenem Sodium Carbonate
Product ID M1770
Cas No. 96036-03-2 (free acid)
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
|---|
Product Info
| Cas No. | 96036-03-2 (free acid) |
|---|---|
| Purity | ≥98% |
| Formula | C17H25N3O5S |
| Formula Wt. | 383.46 |
| Chemical Name | (4R,5S,6S)-3-[[(3S,5S)5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxyloc acid |
| IUPAC Name | (4R,5S,6S)-3-[(3S, 5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1- hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid |
| Synonym | Merrem |
| Solubility | Soluble in water |
| Appearance | White or Off-yellow Crystalline Powder |
Shipping and Storage
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
|---|---|
| Info Sheet |
References
Guzek A, Tomaszewski D, Rybicki Z, et al. Comparison of in vitro efficacy of ertapenem, imipenem and meropenem in the infections caused by the Enterobacteriaceae strains family. Anaesthesiol Intensive Ther. 2013 Apr-Jun;45(2):67-72. PMID: 23877897.
Li WJ, Li DF, Hu YL, et al. Crystal structure of L,D-transpeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis. Cell Res. 2013 May;23(5):728-31. PMID: 23588382.
Louie A, VanScoy BD, Brown DL, et al. Impact of spores on the comparative efficacies of five antibiotics for treatment of Bacillus anthracis in an in vitro hollow fiber pharmacodynamic model. Antimicrob Agents Chemother. 2012 Mar;56(3):1229-39. PMID: 22155821.
Isozumi R, Yoshimatsu K, Yamashiro T, et al. bla(NDM-1)-positive Klebsiella pneumoniae from environment, Vietnam. Emerg Infect Dis. 2012 Aug;18(8):1383-1385. PMID: 22840532.