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N-Acetyl-L-Cysteine

N-Acetyl-L-Cysteine

Product ID A0918
Cas No. 616-91-1
Purity ≥98%
Product Unit SizeCostQuantityStock
10 g $45.60 In stock
25 g $82.00 In stock
100 g $182.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

N-Acetyl-L-cysteine exhibits antioxidative, mucolytic, anti-inflammatory, antiviral, antipsychotic, and neuromodulatory activities. N-Acetyl-L-cysteine has clinically been used to treat acetaminophen overdose; it is occasionally commercially sold as a supplement. N-Acetyl-L-cysteine acts as a scavenger of ROS, decreasing oxidative stress in a variety of models. In vitro, this compound also inhibits TNF-α-induced increases in IL-6 release and NF-κB activation. N-Acetyl-L-cysteine also inhibits hepatitis B virus replication by suppressing viral assembly. Clinically, N-acetyl-L-cysteine displays potential benefit in the treatment of various mood disorders as it modulates reward and reinforcement signaling.

Product Info

Cas No.

616-91-1

Purity

≥98%

Formula

C5H9NO3S

Formula Wt.

163.20

Chemical Name

L-α-Acetamido-β-mercaptopropionic acid

IUPAC Name

(2R)-2-acetamido-3-sulfanylpropanoic acid

Synonym

Acetylcysteine, Brunac, Fabrol, Fluimucil, Fluprowit, Mucosil

Melting Point

106-112°C

Solubility

Soluble in water.

Appearance

White Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A0918 MSDS PDF

Info Sheet

A0918 Info Sheet PDF

References

Lim JH, Lee YM, Park SR, et al. Anticancer activity of hispidin via reactive oxygen species-mediated apoptosis in colon cancer cells. Anticancer Res. 2014 Aug;34(8):4087-93. PMID: 25075033.

Grosicka-Maciąg E, Szumiło M, Czeczot H, et al. Modulation of antioxidant defense system by the dithiocarbamate fungicides Maneb and Zineb in Chinese hamster V79 cells and the role of N-acetyl-L-cysteine. Food Chem Toxicol. 2013 Oct;60:130-4. PMID: 23871785.

Dean O, Giorlando F, Berk M. N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action. J Psychiatry Neurosci. 2011 Mar;36(2):78-86. PMID: 21118657.

Weiss L, Hildt E, Hofschneider PH. Anti-hepatitis B virus activity of N-acetyl-L-cysteine (NAC): new aspects of a well-established drug. Antiviral Res. 1996 Aug;32(1):43-53. PMID: 8863995.

Shibanuma M, Kuroki T, Nose K. Inhibition by N-acetyl-L-cysteine of interleukin-6 mRNA induction and activation of NF kappa B by tumor necrosis factor alpha in a mouse fibroblastic cell line, Balb/3T3. FEBS Lett. 1994 Oct 10;353(1):62-6. PMID: 7926024.

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