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Nedaplatin

Nedaplatin

Product ID N0212
Cas No. 95734-82-0
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $135.10 In stock
10 mg $224.60 In stock
25 mg $428.70 In stock
50 mg $796.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Nedaplatin is a second generation platinum compound that exhibits anticancer chemotherapeutic activity. Nedaplatin is a DNA cross-linking agent that acts by binding the N7 position on guanine residues, inhibiting DNA synthesis and repair.

Product Info

Cas No.

95734-82-0

Purity

≥98%

Formula

C2H8N2O3Pt

Formula Wt.

303.18

IUPAC Name

azanide;2-hydroxyacetic acid;platinum(2+)

Melting Point

130°C

Appearance

Off white to pale yellow green powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

N0212 MSDS PDF

Info Sheet

N0212 Info Sheet PDF

References

Yuan G, Wu L, Huang M, et al. A phase II study of concurrent chemo-radiotherapy with weekly nedaplatin in advanced squamous cell carcinoma of the uterine cervix. Radiat Oncol. 2014 Feb 18;9:55. PMID: 24533532.

Ali I, Wani WA, Saleem K, et al. Platinum compounds: a hope for future cancer chemotherapy. Anticancer Agents Med Chem. 2013 Feb;13(2):296-306. PMID: 22583420.

Poklar N, Pilch DS, Lippard SJ, et al. Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7606-11. PMID: 8755522.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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