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Nerolidol, synthetic

Product ID N1769
Cas No. 7212-44-4
Purity A mixture of cis and trans isomers, ≥96%
Product Unit SizeCostQuantityStock
5 g $35.30 In stock
25 g $61.80 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Nerolidol exhibits neuromodulatory, sedative, antibacterial, antifungal, antioxidative, and anticancer activities. Nerolidol inhibits acetylcholinesterase (AChE) and acts as a sedative in vivo in the open field test. This compound also displays antimicrobial activity against gram negative and gram positive bacteria as well as fungi. In vivo, nerolidol increases superoxide dismutase and catalase activity and decreases lipid peroxidation and nitrite levels in the hippocampus. Additionally, nerolidol modulates F0F1-ATP synthase, decreasing mitochondrial transmembrane electric potential, inhibiting cell growth, and causing death in hepatocarcinoma cells.

Product Info

Cas No.

7212-44-4

Purity

A mixture of cis and trans isomers, ≥96%

Formula

C15H26O

Formula Wt.

222.37

Chemical Name

3,7,11-Trimethyldodeca-1,6,10-trien-3-ol, 3-Hydroxy-3,7,11-trimethyl-1,6,10-dodectriene

IUPAC Name

3,7,11-trimethyldodeca-1,6,10-trien-3-ol

Synonym

Stirrup, Peruviol

Melting Point

-75°C

Solubility

Sparingly soluble in water.

Appearance

Colorless to Pale Yellow Liquid

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

N1769 MSDS PDF

Info Sheet

N1769 Info Sheet PDF

References

Nogueira Neto JD, de Almeida AA, da Silva Oliveira J, et al. Antioxidant effects of nerolidol in mice hippocampus after open field test. Neurochem Res. 2013 Sep;38(9):1861-70. PMID: 23765368.

Tao R, Wang CZ, Kong ZW. Antibacterial/antifungal activity and synergistic interactions between polyprenols and other lipids isolated from Ginkgo biloba L. leaves. Molecules. 2013 Feb 7;18(2):2166-82. PMID: 23434869.

Kang JS, Kim E, Lee SH, et al. Inhibition of acetylcholinesterases of the pinewood nematode, Bursaphelenchus xylophilus, by phytochemicals from plant essential oils. Pestic Biochem Physiol. 2013 Jan;105(1):50-6. PMID: 24238290.

Ferreira FM, Palmeira CM, Oliveira MM, et al. Nerolidol effects on mitochondrial and cellular energetics. Toxicol In Vitro. 2012 Mar;26(2):189-96. PMID: 22138475.

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