• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Neuromedin

Neuromedin

Product ID N1979
Cas No. 102577-25-3
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $65.40 In stock
2 mg $111.60 In stock
5 mg $196.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Neuromedin N is an endogenous proneurotensin peptide involved in energy homeostasis regulation; it modulates hypothalamic thermoregulatory signaling in animal models and induces contraction in ileal smooth muscle cells. Neuromedin N also inhibits reward/reinforcement signaling by inhibiting the intracranial self-stimulation (ICSS) in animal models of reward and reinforcement. Src activates proneurotensin/neuromedin N promoter activity in a Raf-dependent manner. Additionally, neuromedin N is inactivated by dipeptidyl peptidases and aminopeptidases.

Product Info

Cas No.

102577-25-3

Purity

≥95%

Formula

C38H63N7O8

Formula Wt.

745.97

IUPAC Name

(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S,3S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid

Synonym

Neuromedin N

Solubility

Soluble in water (0.5 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

N1979 MSDS PDF

Info Sheet

N1979 Info Sheet PDF

References

Basir YJ, Knoop FC, Dulka J, et al. Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris. Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105. PMID: 11087945.

Banker NA, Hellmich MR, Kim HJ, et al. Src-mediated activation of the human neurotensin/neuromedin N promoter. Surgery. 1997 Aug;122(2):180-6. PMID: 9288121.

Fernández R, Alba F, Ferrer JM. Peptidase inhibitors potentiate the effects of neurotensin and neuromedin N on self-stimulation of the medial prefrontal cortex. Neuroreport. 1996 Feb 29;7(3):798-800. PMID: 8733748.

Barelli H, Woskowska Z, Cipris S, et al. Pharmacological role and degradation processes of neuromedin N in the gastrointestinal tract: an in vitro and in vivo study. J Pharmacol Exp Ther. 1995 Dec;275(3):1300-7. PMID: 8531096.

Malendowicz LK, Nussdorfer GG, Markowska A, et al. Investigations on the acute effects of neuropeptides on the pituitary-adrenocortical function in normal and cold-stressed rats. II. Neurotensin and neuromedin N. Exp Toxicol Pathol. 1995 Jan;47(1):41-5. PMID: 7719120.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C9711

    Cyclovirobuxine D

    Found in Buxus; hERG K+ channel inhibitor.

    ≥97%
  • I5213

    Indole-3-carbinol

    Indole, glucosinolate found in cruciferous vege...

    ≥98%
  • B8174

    Butylated Hydroxyanisole

    Commercial food additive, antioxidant.

    ≥96%
  • M1444

    MDL 29951

    GPR17 agonist, NMDA and fructose 1,6-bisphospha...

    ≥98%
  • A1319

    Adenosine Triphosphate Disodium Hydrate

    Endogenous coenzyme, unit of cellular energy, r...

    ≥95%
  • O938565

    6-Oxodocetaxel

    Docetaxel impurity

    ≥98%
  • K1653

    Kendomycin

    Macrolide; ET antagonist, proteasome inhibitor....

    ≥98%
  • D004098

    Dacomitinib Anhydrous

    EGFR inhibitor.

    ≥99%
  • C3214

    CID-797718

    Potential PKD binding agent.

    ≥99%
  • C2968

    Chrysin

    Flavone found in Passiflora, Oroxylum, and Pleu...

    ≥98%
  • C0145

    Calcitriol

    Active form of vitamin D, regulates dietary Ca2...

    ≥97%
  • M1769

    Meropenem Trihydrate

    β-lactam carbapenem; penicillin binding protei...

    ≥98%
  • D3362

    Dipyridamole

    PDE and adenosine deaminase inhibitor.

    ≥98%
  • P3018

    Phellodendrine

    Quaternary base alkaloid found in Phellodendron...

    ≥98%
  • F334453

    Filipin III

    Antifungal antibiotic

    ≥95%
  • M0114

    Madecassic Acid

    Downregulates LPS-stimulated expression of pro-...

    ≥95%
  • I4000

    Ikarugamycin

    Protein translation inhibitor.

    ≥98%
  • C7692

    CTX IV (6-12)

    Snake venom cardiotoxin found in Naja naja atra...

    ≥98%
  • O1176

    n-Octyl Caffeate

    Caffeic acid derivative.

    ≥98%
  • S1845

    L-(+)-Selenomethionine

    Naturally occurring amino acid found in grains,...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only