Description
Physalaemin is an amphibian tachykinin neuropeptide. This peptide induces contractions in distal colon and esophageal longitudinal muscle in vivo through direct activation of smooth muscle cells and Ca2+ influx.
| Product Unit Size | Cost | Quantity | Stock |
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Physalaemin is an amphibian tachykinin neuropeptide. This peptide induces contractions in distal colon and esophageal longitudinal muscle in vivo through direct activation of smooth muscle cells and Ca2+ influx.
| Cas No. | 2507-24-6 |
|---|---|
| Purity | ≥95% |
| Formula | C58H84N14O16S |
| Formula Wt. | 1265.48 |
| IUPAC Name | 4-[2-[[4-amino-1-[[6-amino-1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1,4-dioxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-oxo-3-[2-[(5-oxopyrrolidine-2-carbonyl)amino]propanoylamino]butanoic acid |
| Solubility | Soluble in water. |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Shiina T, Shima T, Hirayama H, et al. Contractile responses induced by physalaemin, an analogue of substance P, in the rat esophagus. Eur J Pharmacol. 2010 Feb 25;628(1-3):202-6. PMID: 19958761.
Fontaine J, Lebrun P. Contractile effects of substance P and other tachykinins on the mouse isolated distal colon. Br J Pharmacol. 1989 Mar;96(3):583-90. PMID: 2470454.
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