• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Protopanaxatriol

Protopanaxatriol

Product ID P6958
Cas No. 34080-08-5
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $114.20 In stock
5 mg $255.30 In stock
10 mg $428.70 In stock
25 mg $837.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Protopanaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) that exhibits antihypertensive, neuromodulatory, and antioxidative activities. Protopanaxatriol prevents breakdown of vitamin D3 and inhibits GABA-A and GABA-C receptors as well as slow-activating delayed rectifier K+ channels. Protopanaxatriol also stimulates production of eNOS and NO, increasing vascular relaxation and decreasing blood pressure. In animal models of isoproterenol-induced myocardial injury, protopanaxatriol decreases levels of maldionaldehyde and increases activity of superoxide dismutase and glutathione peroxidase.

Product Info

Cas No.

34080-08-5

Purity

≥95%

Formula

C30H52O4

Formula Wt.

476.73

IUPAC Name

(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6,12-triol

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

P6958 MSDS PDF

Info Sheet

P6958 Info Sheet PDF

References

Deb S, Chin MY, Adomat H, et al. Ginsenoside-mediated blockade of 1α,25-dihydroxyvitamin D3 inactivation in human liver and intestine in vitro. J Steroid Biochem Mol Biol. 2014 May;141:94-103. PMID: 24486455.

Lee BH, Hwang SH, Choi SH, et al. Inhibitory Effects of Ginsenoside Metabolites, Compound K and Protopanaxatriol, on GABAC Receptor-Mediated Ion Currents. Korean J Physiol Pharmacol. 2013 Apr;17(2):127-32. PMID: 23626474.

Hong SY, Kim JY, Ahn HY, et al. Panax ginseng extract rich in ginsenoside protopanaxatriol attenuates blood pressure elevation in spontaneously hypertensive rats by affecting the Akt-dependent phosphorylation of endothelial nitric oxide synthase. J Agric Food Chem. 2012 Mar 28;60(12):3086-91. PMID: 22380784.

Lee BH, Choi SH, Shin TJ, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36(1):55-60. PMID: 23717104

Han B, Meng Q, Li Q, et al. Effect of 20(S)-protopanaxatriol and its epimeric derivatives on myocardial injury induced by isoproterenol. Arzneimittelforschung. 2011;61(3):148-52. PMID: 21528638.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C0167

    Carbenoxolone

    Synthetic glycyrrhetinic acid derivative; 11β-...

    ≥98%
  • A6934

    Aristolochic Acid C

    Found in Aristolochia and Radix; potential PLA2...

    ≥94%
  • A9708

    AZD-1208

    Pim-1 inhibitor.

    ≥98%
  • S0170

    Sarafloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥95%
  • B8275

    n-Butyric Acid

    Fatty acid found in dairy products; HDAC inhibi...

    ≥98%
  • M1676

    Methotrexate Hydrate

    DHF reductase inhibitor.

    ≥98%
  • A5134

    Aminophylline Anhydrous

    Adenosine antagonist, PDE inhibitor.

    ≥98%
  • K0038

    Kahweol Oleate

    Diterpene found in coffee beans.

    ≥98%
  • T0251

    Tamsulosin Hydrochloride

    α1-adrenergic antagonist.

    ≥98%
  • S5976

    Sotalol Hydrochloride

    β-adrenergic antagonist, voltage-gated Na+ and...

    ≥98%
  • T0109

    13-Acetyl-9-dihydrobaccatin-III

    Found in Taxus, starting material for synthesis...

    ≥98%
  • R0272

    Rasagiline Mesylate

    MAO-A/B inhibitor.

    ≥98%
  • Y0052

    Yangonin

    Dienolide kavalactone originally found in Piper...

    ≥98%
  • G0180

    Gastrin I, human

    Endogenous peptide hormone involved in feeding ...

    ≥98%
  • N0161

    β-Naphthoflavone

    AhR agonist.

    ≥98%
  • L1852

    Lenalidomide

    Thalidomide derivative; cereblon and TNF-α inh...

    ≥98%
  • P7058

    Protocatechuic Aldehyde

    Polyphenol found in various plants and foods.

    ≥98%
  • I1418

    Idebenone

    Synthetic quinone CoQ analog, promotes mitochon...

    ≥98%
  • M400005

    MK-5108 Hydrochloride

    Aurora kinase A inhibitor.

    ≥98%
  • P0256

    Pantoprazole Sodium Sesquihydrate

    H+/K+ ATPase and ROCK-2 inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only