• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Protopanaxatriol

Protopanaxatriol

Product ID P6958
Cas No. 34080-08-5
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $114.20 In stock
5 mg $255.30 In stock
10 mg $428.70 In stock
25 mg $837.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Protopanaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) that exhibits antihypertensive, neuromodulatory, and antioxidative activities. Protopanaxatriol prevents breakdown of vitamin D3 and inhibits GABA-A and GABA-C receptors as well as slow-activating delayed rectifier K+ channels. Protopanaxatriol also stimulates production of eNOS and NO, increasing vascular relaxation and decreasing blood pressure. In animal models of isoproterenol-induced myocardial injury, protopanaxatriol decreases levels of maldionaldehyde and increases activity of superoxide dismutase and glutathione peroxidase.

Product Info

Cas No.

34080-08-5

Purity

≥95%

Formula

C30H52O4

Formula Wt.

476.73

IUPAC Name

(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6,12-triol

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

P6958 MSDS PDF

Info Sheet

P6958 Info Sheet PDF

References

Deb S, Chin MY, Adomat H, et al. Ginsenoside-mediated blockade of 1α,25-dihydroxyvitamin D3 inactivation in human liver and intestine in vitro. J Steroid Biochem Mol Biol. 2014 May;141:94-103. PMID: 24486455.

Lee BH, Hwang SH, Choi SH, et al. Inhibitory Effects of Ginsenoside Metabolites, Compound K and Protopanaxatriol, on GABAC Receptor-Mediated Ion Currents. Korean J Physiol Pharmacol. 2013 Apr;17(2):127-32. PMID: 23626474.

Hong SY, Kim JY, Ahn HY, et al. Panax ginseng extract rich in ginsenoside protopanaxatriol attenuates blood pressure elevation in spontaneously hypertensive rats by affecting the Akt-dependent phosphorylation of endothelial nitric oxide synthase. J Agric Food Chem. 2012 Mar 28;60(12):3086-91. PMID: 22380784.

Lee BH, Choi SH, Shin TJ, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36(1):55-60. PMID: 23717104

Han B, Meng Q, Li Q, et al. Effect of 20(S)-protopanaxatriol and its epimeric derivatives on myocardial injury induced by isoproterenol. Arzneimittelforschung. 2011;61(3):148-52. PMID: 21528638.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C0140

    Calcitonin, eel

    Endogenous neuropeptide hormone, lowers extrace...

    ≥95%
  • F465818

    Fluorouracil Impurity B

    Fluorouracil impurity

    ≥95%
  • P2410

    Phenethyl Dimethyl Caffeate

    Caffeic acid derivative.

    ≥98%
  • G346851

    Givinostat Hydrochloride

    Non-selective HDAC inhibitor.

    ≥98%
  • Z3463

    Ziprasidone

    5-HT1A agonist, D2, 5-HT1D antagonist.

    ≥98%
  • P1845

    Pelitinib

    EGFR inhibitor.

    ≥98%
  • T6930

    Triclosan Methyl Ether

    Diarylether; bacterial ENR binder, fatty acid s...

    ≥99%
  • F8149

    Fumonisin B1

    Mycotoxin produced by Fusarium; sphingosine acy...

    ≥98%
  • F8270

    Furosemide

    Loop diuretic; NKCC symporter inhibitor, CFTR C...

    ≥97%
  • O486180

    Omeprazole Related Compound A

    Impurity of omeprazole

    ≥99%
  • O1078

    Octreotide Acetate

    Somatostatin analog, peptide; somatostatin agon...

    ≥95%
  • S1609

    Securinine

    Alkaloid found in Securinega; potential GABA-A ...

    ≥98%
  • S6134

    Spinorphin, bovine

    Endogenous heptapeptide; P2X3 and N-formylpepti...

    ≥95%
  • I7456

    1-Isothiocyanato-7-(methylsulfinyl)-heptane

    ITC, radical scavenger.

    ≥98%
  • M3368

    Mirtazapine

    Piperazine; 5-HT1 agonist, 5-HT2/3 and α2-adre...

    ≥98%
  • D3329

    7,8-Dihydroxyflavone Hydrate

    TrkB agonist.

    ≥99%
  • K0022

    K252b

    Staurosporine analog; PKC inhibitor.

    ≥98%
  • S800000

    SU-9516

    CDK2 inhibitor.

    ≥98%
  • SB5778

    Snake venom – Bothrops neuwiedi diporous

    Snake venom found in Bothrops neuwiedi diporus;...

    ≥98%
  • F3209

    Fibronectin-Binding Protein

    Peptide, binds fibronectin.

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only