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Trimebutine Maleate

Trimebutine Maleate

Product ID T6934
Cas No. 34140-59-5
Purity ≥96%
Product Unit SizeCostQuantityStock
1 g $61.10 In stock
5 g $102.00 In stock
25 g $286.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Trimebutine exhibits antibacterial and gastrointestinal motility modulating activities; it is clinically used to treat irritable bowel syndrome (IBS). Trimebutine displays antibiotic activity against Escherichia and Pseudomonas. This compound enhances gastrointestinal muscle contractions by inhibiting L-type Ca2+ channels and decreasing Ca2+-sensitive BK K+ currents and may also act as an agonist at opioid receptors.

Product Info

Cas No.

34140-59-5

Purity

≥96%

Formula

C22H29NO5 • C4H4O4

Formula Wt.

503.54

Chemical Name

3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)- 2-phenylbutyl ester maleate

IUPAC Name

(Z)-but-2-enedioic acid;[2-(dimethylamino)-2-phenylbutyl] 3,4,5-trimethoxybenzoate

Synonym

Cerekinon, Debridat, Digerent, Foldox, Polibutin, Spabucol, Trimedat

Melting Point

105-106°C

Solubility

Slightly soluble in chloroform, methanol. Soluble in water (35 mg/mL), ethanol, DMSO.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T6934 MSDS PDF

Info Sheet

T6934 Info Sheet PDF

References

Kountouras J, Sofianou D, Gavalas E, et al. Trimebutine as a potential antimicrobial agent: a preliminary in vitro approach. Hippokratia. 2012 Oct;16(4):347-9. PMID: 23935315.

Tan W, Zhang H, Luo HS, et al. Effects of trimebutine maleate on colonic motility through Ca²+-activated K+ channels and L-type Ca²+ channels. Arch Pharm Res. 2011 Jun;34(6):979-85. PMID: 21725819.

Custom Order

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