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Pyrazinamide

Pyrazinamide

Product ID P9671
Cas No. 98-96-4
Purity ≥98%
Product Unit SizeCostQuantityStock
10 g $61.10 In stock
25 g $102.00 In stock
100 g $324.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Pyrazinamide is a nicotinamide analog prodrug that exhibits antibiotic activity, inhibiting bacterial fatty acid synthetase I. Pyrazinamide displays antibacterial efficacy against both active and dormant bacteria, disrupting cell membranes, acidifying cytoplasm, and inhibiting membrane transport.

Product Info

Cas No.

98-96-4

Purity

≥98%

Formula

C5H5N3O

Formula Wt.

123.11

IUPAC Name

pyrazine-2-carboxamide

Synonym

Pyrazinecarboxamide, Pyranzinoic acid amide

Melting Point

189-191°C

Solubility

Soluble in water (15mg/mL).

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P9671 MSDS PDF

Info Sheet

P9671 Info Sheet PDF

References

Singh P, Mishra AK, Malonia SK, et al. The paradox of pyrazinamide: an update on the molecular mechanisms of pyrazinamide resistance in Mycobacteria. J Commun Dis. 2006 Mar;38(3):288-98. PMID: 17373362.

Zhang Y, Wade MM, Scorpio A, et al. Mode of action of pyrazinamide: disruption of Mycobacterium tuberculosis membrane transport and energetics by pyrazinoic acid. J Antimicrob Chemother. 2003 Nov;52(5):790-5. PMID: 14563891.

Custom Order

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