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Spectinomycin Dihydrochloride Pentahydrate

Spectinomycin Dihydrochloride Pentahydrate

Product ID S6018
Cas No. 22189-32-8
Purity ≥603 µg/mg (potency)
Product Unit SizeCostQuantityStock
5 g $92.00 In stock
25 g $204.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Spectinomycin is an aminocyclitol antibiotic initially produced by Streptomyces. Spectinomycin binds 16S rRNA of the 30S bacterial ribosome, inhibiting translocation and protein synthesis. Spectinomycin exhibits antibacterial activity and was originally used to treat gonorrhea, but has since been replaced by newer drugs.

Product Info

Cas No.

22189-32-8

Purity

≥603 µg/mg (potency)

Formula

C14H24N2O7 • 2HCl • 5H2O

Formula Wt.

495.25

IUPAC Name

(1R,3S,5R,8R,10R,11S,12S,13R,14S)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one;pentahydrate;dihydrochloride

Synonym

Spectam, Spectinomycin dihydrochloride, Stanilo

Melting Point

~205-207°C (dec)

Solubility

Soluble in water to 100 mM. methanol, propylene glycol, and formamid. DMSO to 99 mg/mL, PBS to 10 mg/mL.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

S6018 MSDS PDF

Info Sheet

S6018 Info Sheet PDF

References

Ilina EN, Malakhova MV, Bodoev IN, et al. Mutation in ribosomal protein S5 leads to spectinomycin resistance in Neisseria gonorrhoeae. Front Microbiol. 2013 Jul 10;4:186. PMID: 23847609.

Kehrenberg C, Schwarz S. Mutations in 16S rRNA and ribosomal protein S5 associated with high-level spectinomycin resistance in Pasteurella multocida. Antimicrob Agents Chemother. 2007 Jun;51(6):2244-6. PMID: 17371823.

Custom Order

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