Description
Sulfadoxine is a sulfonamide anti-parasitic that inhibits dihydropteroate synthase, preventing folate synthesis and increases blood oxygen levels. Sulfadoxine exhibits antimalarial activity and is typically given with pyrimethamine.
Sulfadoxine
Product ID S8144
Cas No. 2447-57-6
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 2447-57-6 |
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| Purity | ≥98% |
| Formula | C12H14N4O4S |
| Formula Wt. | 310.33 |
| Chemical Name | 4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)- benzenesulfonamide |
| IUPAC Name | 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide |
| Synonym | Fanasil, Fanzil, Sulforthomidine |
| Melting Point | 190-194°C |
| Solubility | Soluble in dilute mineral acids, solutions of alkali hydroxides and carbonates. Slightly soluble in water and methanol. |
| Appearance | White Crystal Powder |
Shipping and Storage
| Store Temp | Ambient |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Combrinck JM, Mabotha TE, Ncokazi KK, et al. Insights into the role of heme in the mechanism of action of antimalarials. ACS Chem Biol. 2013 Jan 18;8(1):133-7. PMID: 23043646.
Abebe W. Therapeutic efficacy of sulfadoxin/pyrimethamine in the treatment of uncomplicated Plasmodium falciparum malaria in Enseno, Meskan Woreda, Gurage zone, SNNPR, Ethiopia. Ethiop Med J. 2006 Apr;44(2):133-8. PMID: 17447375.