Description
Tazobactam is a β-lactamase inhibitor that is clinically used to enhance the antibacterial efficacy of β-lactam antibiotics. Tazobactam is especially active against Enterobacter and Staphylococcus.
Tazobactam Sodium
Product ID T0299
Cas No. 89785-84-2
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 89785-84-2 |
|---|---|
| Purity | ≥98% |
| Formula | C10H10N4NaO5S |
| Formula Wt. | 322.28 |
| Chemical Name | (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1- ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid 4,4-dioxide sodium salt |
| IUPAC Name | sodium;(2S,3S,5R)-3-methyl-4,4, 7-trioxo-3-(triazol-1-ylmethyl)-4λ6-thia-1-azabicyclo[3.2.0]heptane- 2-carboxylate |
| Synonym | YTR-830, CL-307579 |
| Melting Point | >170°(dec.) |
| Solubility | Soluble in water. |
| Appearance | White to yellow powder |
Shipping and Storage
| Store Temp | Ambient |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Zhanel GG, Chung P, Adam H, et al. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 2014 Jan;74(1):31-51. PMID: 24352909.
Frase H, Smith CA, Toth M, et al. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. J Biol Chem. 2011 Apr 22;286(16):14396-409. PMID: 21345789.
Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.