Description
Tazobactam is a β-lactamase inhibitor that is clinically used to enhance the antibacterial efficacy of β-lactam antibiotics. Tazobactam is especially active against Enterobacter and Staphylococcus.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Tazobactam is a β-lactamase inhibitor that is clinically used to enhance the antibacterial efficacy of β-lactam antibiotics. Tazobactam is especially active against Enterobacter and Staphylococcus.
| Cas No. | 89785-84-2 |
|---|---|
| Purity | ≥98% |
| Formula | C10H10N4NaO5S |
| Formula Wt. | 322.28 |
| Chemical Name | (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1- ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid 4,4-dioxide sodium salt |
| IUPAC Name | sodium;(2S,3S,5R)-3-methyl-4,4, 7-trioxo-3-(triazol-1-ylmethyl)-4λ6-thia-1-azabicyclo[3.2.0]heptane- 2-carboxylate |
| Synonym | YTR-830, CL-307579 |
| Melting Point | >170°(dec.) |
| Solubility | Soluble in water. |
| Appearance | White to yellow powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Zhanel GG, Chung P, Adam H, et al. Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli. Drugs. 2014 Jan;74(1):31-51. PMID: 24352909.
Frase H, Smith CA, Toth M, et al. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. J Biol Chem. 2011 Apr 22;286(16):14396-409. PMID: 21345789.
Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.
Diterpene found in coffee beans.
PP2A inhibitor.
Tricyclic benzonaphthyridinone; mTORC1/2 inhibi...
Proteasome inhibitor.
HIV protease inhibitor, SERCA inhibitor.
Diterpene found in brewed, unfiltered coffee; F...
Nucleoside (cytidine) analog; RT and telomerase...
Diphenylmethane, inhibits secretion of cortisol...
Pyridine; PDE3 inhibitor.
Endogenous calcitonin-family peptide, involved ...
Mixture of Ginkgolides A, B and C, found in Gin...
Resveratrol prodrug; potential SIRT1 activator....
Marine toxin; actin polymerization inducer.
Semi-synthetic avermectin; GABA potentiator.
Ergot derivative found in Claviceps; α1-adrene...
Endogenous peptide fragment, immunostimulant; ...
Recombinant HIV glycoprotein antigen fragment.<...
Nitrofuran, livestock antibiotic.
Sulforaphane-cysteine conjugate.