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C-type Natriuretic Peptide (1-22), pig/human/rat

C-type Natriuretic Peptide (1-22), pig/human/rat

Product ID C5260
Cas No.
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $481.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

C-type natriuretic peptide (CNP) is an endogenous peptide expressed in the central nervous system, bone, and vasculature; CNP-22 is a mature form of CNP that is found predominantly in plasma. CNP exhibits vasodilatory, natriuretic, diuretic, and cardioprotective activities. CNP also exhibits anti-fibrotic potential, regulating cardiac hypertrophy and remodeling. This peptide inhibits the renin-angiotensin system, increasing endothelial permeability, and plays a role in bone growth.

Product Info

Purity

≥95%

Formula

C93H157N27O28S3

Formula Wt.

2197.61

Synonym

CNP

Solubility

Soluble in water (1 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

C5260 Info Sheet PDF

References

Del Ry S. C-type natriuretic peptide: a new cardiac mediator. Peptides. 2013 Feb;40:93-8. PMID: 23262354.

Calvieri C, Rubattu S, Volpe M. Molecular mechanisms underlying cardiac antihypertrophic and antifibrotic effects of natriuretic peptides. J Mol Med (Berl). 2012 Jan;90(1):5-13. PMID: 21826523.

Nishikimi T, Kuwahara K, Nakao K. Current biochemistry, molecular biology, and clinical relevance of natriuretic peptides. J Cardiol. 2011 Mar;57(2):131-40. Erratum in: J Cardiol. 2012 Jan;59(1):98-9. PMID: 21296556.

Del Ry S, Passino C, Emdin M, et al. C-type natriuretic peptide and heart failure. Pharmacol Res. 2006 Nov;54(5):326-33. PMID: 16904335.

Custom Order

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