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Cefoperazone Sodium

Product ID C1630
Cas No. 62893-20-3
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $92.50 In stock
5 g $305.70 In stock
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  • Product Info
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  • Description
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Description

Cefoperazone is a third generation β-lactam cephalosporin antibiotic. Cefoperazone exhibits antibacterial efficacy against gram positive and gram negative bacteria, inhibiting penicillin binding proteins to prevent peptidoglycan synthesis and bacterial cell wall formation. Cefoperazone also inhibits mammalian mRNA splicing and is often given in combination with the β-lactamase sulbactam.

Product Info

Cas No.

62893-20-3

Purity

≥98%

Formula

C25H26N9NaO8S2

Formula Wt.

667.65

Chemical Name

(6R,7R)-7-[[(2R)-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)- carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3- [[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5- thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt

IUPAC Name

sodium;(6R,7R)-7-[[(2R)-2-[(4-ethyl-2, 3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[ (1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylate

Synonym

Bioperazone, Cefazone, Cefobis, Cefoneg, Farecef, Novobiocyl, Perocef

Melting Point

200-202°C

Solubility

Soluble in water to 75 mM.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C1630 MSDS PDF

Info Sheet

C1630 Info Sheet PDF

References

Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919.

Mohanty S, Singhal R, Sood S, et al. Comparative in vitro activity of beta-lactam/beta-lactamase inhibitor combinations against gram negative bacteria. Indian J Med Res. 2005 Nov;122(5):425-8. PMID: 16456257.

Yotsuji A, Mitsuyama J, Hori R, et al. Mechanism of action of cephalosporins and resistance caused by decreased affinity for penicillin-binding proteins in Bacteroides fragilis. Antimicrob Agents Chemother. 1988 Dec;32(12):1848-53. PMID: 3266730.

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