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Thymosin α-1

Thymosin α-1

Product ID T3096
Cas No. 62304-98-7
Purity ≥95%
Product Unit SizeCostQuantityStock
10 mg $572.50 In stock
50 mg $1,788.50 In stock
1 g $8,176.60 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Thymosin α-1 is an endogenous immunostimulatory peptide that is used to treat immune deficiency diseases and to enhance vaccine immunogenicity. Thymosin α-1 enhances T-cell, dendritic cell, and antibody responses in vitro and inhibits steroid-induced thymocyte apoptosis. During transplants, thymosin α-1 activates indoleamine 2,3-dioxygenase, promoting immune tolerance. In vitro, this peptide modulates CD4+ CD25+ Foxp3+ Treg cells and pro-inflammatory cytokine levels.

Product Info

Cas No.

62304-98-7

Purity

≥95%

Formula

C129H215N33O55

Formula Wt.

3108.3

Synonym

Thymalfasin, Zadaxin

Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

T3096 MSDS PDF

Info Sheet

T3096 Info Sheet PDF

References

Tuthill C, Rios I, De Rosa A, et al. Thymosin α1 continues to show promise as an enhancer for vaccine response. Ann N Y Acad Sci. 2012 Oct;1270:21-7. PMID: 23050813.

Romani L, Moretti S, Fallarino F, et al. Jack of all trades: thymosin α1 and its pleiotropy. Ann N Y Acad Sci. 2012 Oct;1269:1-6. PMID: 23045964.

Yang X, Qian F, He HY, et al. Effect of thymosin alpha-1 on subpopulations of Th1, Th2, Th17, and regulatory T cells (Tregs) in vitro. Braz J Med Biol Res. 2012 Jan;45(1):25-32. PMID: 22245858.

Wan J, Shan Y, Shan H, et al. Thymosin-alpha1 promotes the apoptosis of regulatory T cells and survival rate in septic mice. Front Biosci (Landmark Ed). 2011 Jun 1;16:3004-13. PMID: 21622217.

Custom Order

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