Cromolyn Sodium

Name: Cromolyn Sodium
SKU: C6955
Availability: InStock

Product ID C6955

Cas No. 15826-37-6

Purity ≥99%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Cromolyn sodium is a mast cell stabilizer that prevents mast cell degranulation and histamine release. Cromolyn sodium may also inhibit transient receptor potential (TRP) channels on C fibers and act as an antagonist at Cl- channels. Cromolyn sodium activates phosphorylation of PKC and release of annexin A1, exhibiting anti-allergic, anti-asthma, and anti-inflammatory activities. This compound also inhibits release of pro-inflammatory cytokines. In animal models of myocarditis, cromolyn sodium displays cardioprotective benefit, preventing left ventricular remodeling and dysfunction.

Product Info

Cas No.	15826-37-6
Purity	≥99%
Formula	C₂₃H₁₄O₁₁Na₂
Formula Wt.	512.3
Chemical Name	5,5'-[(2-Hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-4H-1-benzopyran-2-carboxylic acid] disodium salt
IUPAC Name	disodium;5-[3-(2-carboxylato-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4- oxochromene-2-carboxylate
Synonym	Cromolyn disodium salt, Aarane, Alerion, Allergocrom, Cromovet, Fivent, Inostral, Introl, Lomudal, Lomuspray, Nasmil, Opticrom, Rynacrom, Sofro, Vividrin
Melting Point	240-242°C
Solubility	Soluble in water.
Appearance	White to off white powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	C6955 MSDS PDF
Info Sheet	C6955 Info Sheet PDF

References

Zhang A, Chi X, Luo G, et al. Mast cell stabilization alleviates acute lung injury after orthotopic autologous liver transplantation in rats by downregulating inflammation. PLoS One. 2013 Oct 8;8(10):e75262. PMID: 24116032.

Yazid S, Sinniah A, Solito E, et al. Anti-allergic cromones inhibit histamine and eicosanoid release from activated human and murine mast cells by releasing Annexin A1. PLoS One. 2013;8(3):e58963. PMID: 23527056.

Mina Y, Rinkevich-Shop S, Konen E, et al. Mast cell inhibition attenuates myocardial damage, adverse remodeling, and dysfunction during fulminant myocarditis in the rat. J Cardiovasc Pharmacol Ther. 2013 Mar;18(2):152-61. PMID: 23172937.

Yazid S, Leoni G, Getting SJ, et al. Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization. Arterioscler Thromb Vasc Biol. 2010 Sep;30(9):1718-24. PMID: 20558817.

Heinke S, Szücs G, Norris A, et al. Inhibition of volume-activated chloride currents in endothelial cells by chromones. Br J Pharmacol. 1995 Aug;115(8):1393-8. PMID: 8564197.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Comments
This field is for validation purposes and should be left unchanged.

Cromolyn Sodium

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Kemptide

Salmon Calcitonin Acetate

SR1001

Recombinant Zika Virus NS1 Antigen

Cefaclor Monohydrate

VS-5584

Voriconazole

Secretin, rat

Heptaplatin

LXS-196

Catharanthine Tartrate

Ginsenoside Rc

Atomoxetine Hydrochloride

α-Endorphin

Hexamethonium Bromide Hydrate

Sulfasalazine

Roscovitine

Glabridin

4-Phenylbutylisothiocyanate

AT-7519 Hydrochloride

Footer