Tolvaptan

Name: Tolvaptan
SKU: T5847
Availability: InStock

Product ID T5847

Cas No. 150683-30-0

Purity ≥99%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Tolvaptan is an inhibitor of the vasopressin receptor subtype V2; it acts as a diuretic, inhibiting reabsorption of water in the kidney without loss of sodium. Tolvaptan is a clinically effective diuretic used in congestive heart failure (CHF) and severe chronic kidney disease that does not induce hypernatremia. This compound can also be used to treat the severe or chronic hyponatremia stemming from syndrome of inappropriate antidiuretic hormone secretion (SIADH) that occurs after traumatic brain injury.

Product Info

Cas No.	150683-30-0
Purity	≥99%
Formula	C₂₆H₂₅ClN₂O₃
Formula Wt.	448.94
Chemical Name	N-(4-{[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide
IUPAC Name	N-[4-(7-chloro-5-hydroxy-2,3,4, 5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide
Synonym	OPC-41061
Melting Point	226°C
Appearance	Off-white to yellow powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	T5847 MSDS PDF
Info Sheet	T5847 Info Sheet PDF

References

Otsuka T, Sakai Y, Ohno D, et al. The effects of tolvaptan on patients with severe chronic kidney disease complicated by congestive heart failure. Clin Exp Nephrol. 2013 Mar 13. [Epub ahead of print]. PMID: 23483323.

Graziani G, Cucchiari D, Aroldi A, et al. Syndrome of inappropriate secretion of antidiuretic hormone in traumatic brain injury: when tolvaptan becomes a life saving drug. J Neurol Neurosurg Psychiatry. 2012 May;83(5):510-2. PMID: 22323742

Gheorghiade M, Teerlink JR, Mebazaa A. Pharmacology of new agents for acute heart failure syndromes. Am J Cardiol. 2005 Sep 19;96(6A):68G-73G. PMID: 16181825.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Email
This field is for validation purposes and should be left unchanged.

Tolvaptan

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Ergosterol

Butylated Hydroxyanisole

Nitrendipine

RF-NH2

Clomipramine Hydrochloride

Oxibendazole

3′-Azido-3′-deoxythymidine

GDC-0068

17-Dimethylaminoethylamino Demethoxygeldanamycin

5,6-Dehydrokawain

Glucagon (19-29), human

Tunicamycin

Forskolin

p-Xyleneselenocyanate

Withaferin A

BYL719

Eprinomectin

Ketoconazole

Alytesin

Flavokawain A

Footer