• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Ubenimex

Ubenimex

Product ID U0618
Cas No. 58970-76-6
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $54.20 In stock
50 mg $237.90 In stock
100 mg $474.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ubenimex, also known as bestatin, is a dipeptide inhibitor of aminopeptidases such as aminopeptidase N/CD13. Bestatin displays efficacy in the treatment of lung cancer. This compound exhibits anticancer chemotherapeutic, immunomodulatory, and analgesic activities. Bestatin enhances differentiation of acute promyelotic leukemia (APL) cells. Additionally, bestatin enhances proliferation of bone marrow macrophage progenitor cells and formation of CFU-GM colonies. This compound also inhibits catabolism of opioid endopeptides.

Product Info

Cas No.

58970-76-6

Purity

≥98%

Formula

C16H24N2O4

Formula Wt.

308.37

Chemical Name

N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4phenylbutyl]-L-leucine

IUPAC Name

(2S)-2-[[(2S, 3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid

Synonym

Bestatin

Melting Point

233-236°C

Solubility

Soluble in acetic acid, DMSO and methanol. Less soluble in water. Insoluble in ethyl acetate, benzene, hexane and chloroform.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

U0618 MSDS PDF

Info Sheet

U0618 Info Sheet PDF

References

Hitzerd SM, Verbrugge SE, Ossenkoppele G, et al. Positioning of aminopeptidase inhibitors in next generation cancer therapy. Amino Acids. 2014 Apr;46(4):793-808. PMID: 24385243.

Qian X, He J, Zhao Y, et al. Inhibition of p38 MAPK Phosphorylation Is Critical for Bestatin to Enhance ATRA-Induced Cell Differentiation in Acute Promyelocytic Leukemia NB4 Cells. Am J Ther. 2013 Oct 17. [Epub ahead of print]. PMID: 24141198.

Jia MR, Wei T, Xu WF. The Analgesic Activity of Bestatin as a Potent APN Inhibitor. Front Neurosci. 2010 Jun 28;4:50. PMID: 20631848.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B5561

    B-type Natriuretic Peptide (1-32), human

    Endogenous cardiomodulatory peptide; NPR-A agon...

    ≥97%
  • A0778

    ABT-737

    BH3 mimetic; Bcl-2, Bxl-xl, Bcl-w inhibitor.

    ≥98%
  • S7717

    Sterigmatocystin

    Mycotoxin produced by Aspergillus; carcinogen.<...

    ≥98%
  • T9946

    Tylosin Phosphate

    Macrolide; peptidyl transferase inhibitor, prot...

    ≥90%
  • A5314

    Dehydroandrographolide

    Labdane diterpene found in Andrographis.

    ≥98%
  • P0397

    Pazopanib

    VEGFR, PDGFR, c-Kit inhibitor.

    ≥97%
  • N0163

    2-(1,8-Naphthyridin-2-yl)phenol

    Naphthalene; indirect STAT1 agonist.

    ≥98%
  • L5822

    Lofexidine Hydrochloride

    α2-adrenergic agonist.

    ≥98%
  • H9862

    Hypothemycin

    Polyketide found in Setophoma.

    ≥96%
  • A724091

    Asciminib

    Allosteric inhibitor

    ≥98%
  • A4646

    ALLN

    Calpain I/II inhibitor.

    ≥98%
  • G7443

    GSK-429286A

    ROCK1/2 inhibitor, potential RSK and p70S6K inh...

    ≥98%
  • S1848

    Se-Methylseleno-L-cysteine

    Found in plants in Astragalus, Allium, and Bras...

    ≥98%
  • T3454

    Tinidazole

    Nitroimidazole, binds DNA; nucleic acid synthes...

    ≥98%
  • I6932

    Irinotecan

    Camptothecin analog; topoisomerase I inhibitor,...

    ≥98%
  • Z161024

    α-Zearalenol

    Mycotoxin that has structural similarity to est...

    ≥98%
  • H9662

    Hypocrellin B

    Induces DNA strand breakage.

    ≥98%
  • T0108

    10-Deacetyl-7-xylosyltaxol

    Taxane found in species of Taxus; potential mic...

    ≥98%
  • S6800

    SR1001

    RORα/γ inverse agonist.

    ≥99%
  • C577524

    Concanamycin A

    Macrolide lactone antibiotic.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only