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Ceftazidime Hydrate

Product ID C1635
Cas No. 78439-06-2
Purity ≥97%
Product Unit SizeCostQuantityStock
1 g $90.00 In stock
5 g $285.00 In stock
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ceftazidime is a third generation β-lactam cephalosporin antibiotic. Ceftazidime exhibits antibacterial efficacy against most gram positive and some gram negative bacteria, inhibiting penicillin binding proteins to prevent peptidoglycan synthesis and bacterial cell wall formation.

Product Info

Cas No.

78439-06-2

Purity

≥97%

Formula

C22H22N6O7S2 • 5H2O

Formula Wt.

635.65

Chemical Name

1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)- [(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinum inner salt

IUPAC Name

(6R,7R)-7-[[(2Z)-2-(2-amino-1, 3-thiazol-4-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-3- (pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2- carboxylate

Synonym

GR-20263, Fortum

Solubility

Slightly soluble in water, 360 mg/L, ethanol 0.2 mg/mL, DMSO 0.2 mg/mL.

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

C1635 MSDS PDF

Info Sheet

C1635 Info Sheet PDF

References

Chantratita N, Rholl DA, Sim B, et al. Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17165-70. PMID: 21969582.

Phelps DJ, Carlton DD, Farrell CA, et al. Affinity of cephalosporins for beta-lactamases as a factor in antibacterial efficacy. Antimicrob Agents Chemother. 1986 May;29(5):845-8. PMID: 3524432.

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