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WY-14643

WY-14643

Product ID W9602
Cas No. 50892-23-4
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $47.30 In stock
50 mg $118.30 In stock
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Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

WY-14643 is a peroxisome proliferator-activated receptor agonist that has been found to upregulate hepatic gene expression in mouse livers. Furthermore, WY-14643 has been shown to improve proteasomal function, prevent NF-kB activation, and decrease oxidative stress in wild-type and adipose triglyceride lipase knockout mice.

Product Info

Cas No.

50892-23-4

Purity

≥98%

Formula

C14H14ClN3O2S

Formula Wt.

323.80

Chemical Name

2-[4-chloro-6-(2,3-dimethylanilino)pyrimidin-2-yl]sulfanylacetic acid

IUPAC Name

({4-Chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl}sulfanyl)acetic acid

Synonym

Pirinixic Acid, WY14643

Melting Point

155-157°C

Solubility

DMSO (40 mg/ml)

Appearance

Off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

W9602 MSDS PDF

Info Sheet

W9602 Info Sheet PDF

References

Szalowska E, Tesfay HA, van Hijum SA, Kersten S. Transcriptomic signatures of peroxisome proliferator-activated receptor (PPAR) in different mouse liver models identify novel aspects of its biology. BMC Genomics. 2014 Dec; 15(1): 1106. PMID: 25511156.

Mussbacher M, Stessel H, Wolkart G, et al. Role of the ubiquitin-proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice. J Mol Cell Cardiol. 2014 Dec; 77:11-19. PMID: 25285770.

Custom Order

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