Description
Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.
Product Unit Size | Cost | Quantity | Stock |
---|
Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.
Cas No. | 1345847-93-9 |
---|---|
Purity | ≥98% |
Formula | C26H21F3N4O4 |
Formula Wt. | 510.46 |
Chemical Name | 1-N'-[4-[2-(cyclopropanecarbonylamino)pyridin-4-yl]oxy-2,5-difluorophenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide |
IUPAC Name | N-[4-({2-[(Cyclopropylcarbonyl)amino]-4-pyridinyl}oxy)-2,5-difluorophenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
Synonym | DCC-2701, DP-5164 |
Solubility | DMSO: 33mg/mL |
Store Temp | Ambient |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Kwon Y, Smith BD, Zhou Y, et al. Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment. Oncogene. 2015 Jan 8;34(2):144-53. PMID: 24362531.
Fluoroquinolone; vacuolar H+ ATPase, topoisomer...
5-FU prodrug; thymidylate synthase inhibitor.
T-type Ca2+ and voltage-gated Na+ channel block...
Isoflavone daidzein derivative found in Puerari...
Cephalosporin analogue
Peptide; PAR1 agonist.
Insecticide; α-adrenergic agonist, MAO inhibit...
Fibrate; PPARα agonist.
Non-nitrogen bisphosphonate; mitochondrial ATP/...
Histamine H2 inverse agonist.
Nitrofuran derivative.
Synthetic antioxidant that induces phase II enz...
Found in parsley.
Antimicrobial peptide found in frogs, induces p...
Natriuretic, vasodilatory peptide fragment; B1/...
Prenylated phenolic terpene found in various pl...
Antiviral againt SARS-CoV-2
CDK1/2 inhibitor.
MET and Ron inhibitor.
Diterpene found in Taxus.